234 search results for “johan” in the Public website
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University Council
The University Council is the central co-participation body of the University.
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Romy Heymans: fighting back against fake news
Fake news is becoming more and more prominent now that social media allow for an endless stream of unfiltered content to reach us. But what happens if we can no longer distinguish the truth from the lie?
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Expertise, Policy-making and Democracy
This book offers a concise and accessible introduction to debates about expertise, policy-making and democracy. It uniquely combines an overview of recent research on the policy role of experts with discussions in political philosophy and the philosophy of expertise.
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Circulating cells as biomarkers in cardiovascular disease : the difference between men and women
Promotor: J. Kuiper
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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CD8+ T-cells in atherosclerosis, recognizing their contribution
Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.
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Multidominance, ellipsis, and quantifier scope
This dissertation provides a novel perspective on the interaction between quantifier scope and ellipsis. It presents a detailed investigation of the scopal interaction between English negative indefinites, modals, and quantified phrases in ellipsis. One of the crucial observations is that a negative…
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Dyslipidemia, metabolism and autophagy: antigen-independent modulation of T cells in atherosclerosis
Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.
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Mast cells in advanced atherosclerosis: from human plaque stability to new therapeutic targets
In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.
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Transcriptional regulation of monoterpenoid indole alkaloid biosynthesis in Catharanthus roseus
Catharanthus roseus (Madagascar periwinkle) produces valuable monoterpenoid indole alkaloids (MIAs) such as vincristine and vinblastine, crucial for cancer treatment.
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Exploring novel regulators and enzymes in salicylic acid-mediated plant defense
Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.
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Typological tendencies in verse and their cognitive grounding
On May 3rd, Varun de Castro Arrazola succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Varun on this great result.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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The typology and formal semantics of adnominal possession
On May 2nd, Elena Karvovskaya succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Elena on this great result.
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Pluractionality in Hausa
This dissertation addresses the semantics of pluractional verbs in Hausa.
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Vaccination and Targeted Therapy Using Liposomes; Opportunities for Treatment of Atherosclerosis and Cancer
This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.
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Service desk WSD
Lipsius, Cleveringaplaats 1, 2311 BD, Leiden
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Representative Bureaucracy in the Age of Artificial Intelligence (AI)
How and to what extent does AI affect citizen representation in public service delivery and state-citizen interactions?
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Characterization of age-associated immunity in atherosclerosis
Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax
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Mast cells as immune regulators in atherosclerosis
Cardiovascular syndromes are the major cause of death in Western societies.
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The nature of evidentiality
This project launches a research program into the theoretical status and the terminological basis of evidentiality systems.
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More JAZ in the orchestration of jasmonate-mediated plant defense
Promotor: Prof.dr. J. Memelink
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The role of the interleukin 12 family in atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager
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SAILS Lunch Time Seminar: Derya Soydaner
Lecture
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The syntax of verbal pseudo-coordination in English and Afrikaans
This dissertation provides a systematic description of English and Afrikaans verbal pseudo-coordination and a formal analysis couched in the Minimalist program.
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The Legacy of Dutch Brazil
This book argues that Dutch Brazil (1624–54) is an integral part of Atlantic history and that it made an impact well beyond colonial and national narratives in the Netherlands and Brazil.
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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Thorbecke beurs
Luuk van Middelaar and Vestert Borger, both affiliated with the Europa Institute of Leiden University, are conducting a research project that is financed by the Statesman Thorbecke Fund Programme of the Royal Netherlands Academy of Arts and Sciences (KNAW). The aim of the fund is to promote knowledge…
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Towards a feminist playology: social sport studies and the limits of critique
The making of sacrifices seems part and parcel of any elite sportsperson’s life. Remarkably, the insights that we find in the current literature in social sport studies are not able to make sense of the references to sacrifice in the data that emerged in the context of this study on the social significance…
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The evolution of chemical diversity in plants : pyrrolizidine alkaloids and cytochrome P450s in Jacobaea
Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.
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Constitutional and administrative law
Constitutional and administrative law covers a broad area of law. It provides the rules with which issues in society can be solved by government authorities.
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Operators in the lexicon. On the negative logic of natural language
Operators in the Lexicon opens with an old chestnut: why are there no natural single word lexicalizations for negations of the propositional operator and and the predicate calculus operator all: why neither *nand nor *nall?
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Clause-typing and evidentiality in Ecuadorian Siona
This dissertation presents an in-depth study of the clause-typing system in Ecuadorian Siona.
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Mast cell-mediated immune modulation in experimental Rheumatoid Arthritis and Atherosclerosis
In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.
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On the nature of preverbal Focus in Greek. A theoretical and experimental approach
This thesis aims at contributing to our understanding of the semantic and prosodic properties of object foci in Greek, employing theoretical and experimental tools.
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Gradability in the nominal domain
This dissertation investigates whether and how gradability is manifested in the nominal domain, as well as the implications this could have for theories of the representation of gradability.
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The acquisition of verbal morphology in cochlear-implanted and specific language impaired children
This dissertation aims at enhancing our knowledge of whether a CI provides sufficient access to auditory speech input to acquire verbal morphology by comparing outcomes of CI children to those of their normal hearing peers and to those of children with specific language impaired (SLI).
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The evolution of the diversity of secondary metabolites
Why do plants produces always produced so many slightly differing metabolites within a particular chemical class?
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Yes/no question-marking in Italian dialects - A typological, theoretical and experimental approach
This dissertation provides an account of polar questions in Italian dialects from a typological, theoretical and empirical perspective.
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Are Citizens More Negative About Failing Service Delivery by Public Than Private Organizations?
Petra van der Bekerom, Joris van der Voet, and Johan Christensen, three assistant professors at Leiden University, conducted a large-scale survey experiment about whether citizens are more negative about failing service delivery than private organizations.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Famous Leiden scientists
The oldest university in the Netherlands has produced many well-known scientists. Some of them are known to the wider public; others are perhaps less well known, but their achievements are no less impressive.