The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The aim of the project is to unravel the genetic and contact relations between the indigenous languages of Mesoamerica (Mexico and western Central America) and the Middle Andes region (Ecuador, Peru, Bolivia), as part of a larger endeavor to understand the historical process of the peopling of the Americas…

How might viola and string quartet playing in the performer-centered, moment-to-moment and communicative style heard on early recordings be brought about today?

The following dissertation reconstructs Paul Natorp's philosophical psychology. It argues that psychology's main object is the lived experience of concrete subjects, understood as a transcendental structure of logical-reflexive conditions for the recognition, appropriation, and evaluation of objective…

Antibiotic-resistant bacteria are a major problem worldwide. Molecular biologist Changsheng Wu explored innovative methods of developing new antibiotics more simply and more easily. He also discovered a new type of antibiotic.

Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…

Gerard van Westen and his group, together with pharmaceutical company Galapagos, start on developing software that invents new effective molecules. They will receive an NWO LIFT grant of 280,000 euros, of which 63,000 euros will come from Galapagos. The company will also bring its expertise in biology,…

A new way to decipher the light from distant worlds could give us unmistakable evidence of extraterrestrial photosynthesis, and maybe alien plants, finds astronomy author Colin Stuart in the New Scientist. In his article, he describes the work of the group led by Leiden astronomer Rob van Holstein.…

Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.

PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…

If there is life outside our galaxy, how could we find it? In his Oort Lecture, James Kasting talks about his search for simple life on other planets. Kasting was in the Netherlands for two weeks, because he was invited as the Oort Professor 2018.

On 20 April 2017 Jorrit Rijpma, Eugenio Cusumano, and Melanie Fink organise a Workshop to discuss the legal and policy implications of the surge in privately conducted search and rescue operations in the Central Mediterranean. The Workshop takes place in cooperation between the Law School and the Faculty…

Combining geometry and number theory. That is what Dr Jan Vonk of the Institute of Mathematics receives a Vidi grant for today. ‘By fusing these two disciplines we may be able to solve a century-old mathematical problem.’

A vaccine based on sugar coats does have the potential to combat a multi-resistant staphylococcus. That is what Jeroen Codée and his colleagues from Utrecht state in Nature. In doing so, they are contradicting the earlier conclusions of German colleagues.

In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…

Promotor: C. W. J. Beenakker, Co-promotor: J. K. Asboth

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Promotor: C.W.J. Beenakker, Co-promotor: M.T. Wimmer

In unconventional high temperature superconductors, supercurrent vortices are known to spoil the Landau levels. In this thesis the emergence of Landau levels is studied in different types of superconductors: Weyl superconductors, and the Fu-Kane heterostructure.

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

What role do the soil and soil organisms play in the restoration of nature quality? This is what researchers at Leiden University are going to find out, together with water company and nature manager Dunea. They will do this by inoculating soil, whether or not sterilized, with soil and seeds. On Friday…

In the discs of dust and gasses around young stars, mysterious structures occur. Together with professor Ewine van Dishoeck, PhD student Paolo Cazzoletti investigate how we can explain these forms, such as rings, spirals and holes. On 12 December, he will defend his thesis.

Comparison between babies and song-birds when they are learning a non-existent language—a study of this kind has never been tried before. But this is what Claartje Levelt, Carel ten Cate (Leiden University) and Jelle Zuidema (University of Amsterdam) are attempting.

How does ICT affect society? Mirjam van Reisen, professor Computing for Society at the Leiden Centre of Data Science, is intrigued by this question. We speak with her about innovation, changes in health care, and mobile human trafficking. ‘Innovation has many benefits, but it can also be very disrup…

In the period between the First and the Second World War, many Muslim intellectuals came to Europe. What impact did they have on each other’s, as well as on European thinking, and how were they in turn influenced? Leiden Islam expert Dr Umar Ryad has been awarded an ERC Starting Grant to investigate…

Leiden University has signed a substantial number of Memoranda of Understanding with institutions in Latin America and the Caribbean Region.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This research proposal focuses on the investigation of the poetic potentials of negativity through the exploitation of failure in sound based artistic practices - a context that has not been extensively addressed.

Since 1990 Leiden University has awarded the William of Orange medal to individuals of eminent national or international social standing.

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

This thesis covers various applications of topology in condensed matter physics and quantum information.

After decades of intensive farming, the peatland area is under pressure. Researchers, farmers and policymakers work together in the Polderlab to identify future-proof types of agriculture. ‘It’s unbelievable how quickly the system bounces back without intensive fertilisation.’

Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…

On 7 November 2024, an ESIL Joint Colloquium, organised by the European Society of International Law (ESIL) Interest Group ‘The EU as a Global Actor’ (IG EUGLOBAL), in partnership with the Interest Group on Migration and Refugee Law (IG MigRefLaw), took place on the topic ‘The EU as an (Imperfect) Global…

This dissertation examines the airs sérieux contained within the Recueils d’airs serieux et a boire de differents autheurs published by the Ballard printing house in Paris between 1695 and 1699 inclusive.

This edited volume by Jeff Fynn-Paul pushes forward the debate on the role of entrepreneurs in making war and building states in Europe and the Ottoman Empire.

Understanding interactions in quantum many-body systems remains one of the most profound and difficult challenges in condensed matter physics.

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

This project maps the policy of ‘Paz Total’ (Total Peace) and ongoing peace negotiations between non-state armed groups and the government of Colombia under the presidency of Gustavo Petro (2022-2026).

Promotor: C.W.J. Beenakker, Co-Promotor: A.R. Akhmerov

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.