Proceedings of the 25th International Congress of Roman Frontier Studies 2

How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?

The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

What are the key technical, social, regulatory, economic, and ethical considerations for scaling up ocean-based Carbon Dioxide Removal (CDR) approaches, and what integrated assessment frameworks and governance structures are needed to facilitate their implementation at scale?

What is effective viewing behavior for foreign language learners and how can teachers effectively train language learners to apply effective viewing strategies that will maximize their learning when viewing subtitled materials?

On 23 June 2020, Santy Kouwagam defended her PhD-thesis 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. The doctoral research was supervised by Prof. A.W. Bedner and Prof. C.E. von Benda-Beckmann.

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

In this article, Tom Buitelaar proposes a systematic framework for analyzing the impact of individual characteristics of peacekeeping leaders on the behaviour of field-level personnel in UN peacekeeping operations.

Promotor: Prof.dr. T. Hankemeier, Co-promotor: R.J. Vreeken

CML report 192

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Promotores: G. Persoon, R. Schefold

On February 20th, Gulnaz Sibgatullina succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Gulnaz on this great result.

In The Agency of Empire: Connections and Strategies in French Expansion (1686-1746) Elisabeth Heijmans places directors and their connections at the centre of the developments and operations of French overseas companies.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…

This PhD project investigates the argumentative-rhetorical strategies by which the Russian state attempts to substantiate the legitimacy of its war against Ukraine.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

The article offers a comparative systematic literature review of the principles, norms, and strategies associated with Security by Design and Privacy by Design

How did interests outside the scope of the Dutch chartered trading companies influence the career-paths of Dutch colonial governors?

On a referendum held on May 21, 2006, 55.5% of voters in Montenegro voted in favor of their country’s independence. While in numerical terms the outcome shows overwhelming support for independent Montenegro, from a normative standpoint it was a narrow win. The normative framework that regulated rules…

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Patients share valuable advice and experiences with their peers in online patient discussion groups.

This open access volume surveys the state of the field to examine whether a fifth wave of deterrence theory is emerging. Bringing together insights from world-leading experts from three continents, the volume identifies the most pressing strategic challenges, frames theoretical concepts, and describes…

Scientific director Herman Spaink brought almost all scientific staff members of our institute together in Noordwijkerhout for a two-day meeting about strategies for the future.

The Leiden-Delft-Erasmus Centre for BOLD Cities uses multidisciplinary big data research to help find solutions for urban problems. ‘BOLD’ stands for ‘Big, Open and Linked Data’. Data science is one of the Centre’s main disciplines.

Just like every other organism on Earth, plants’ ultimate goal is to survive and reproduce. In order to achieve this, they must make trade-offs between where and how to allocate their finite set of resources. Whether they put their resources and energy into their growth, reproduction or maintenance,…

The threats from North Korea have become so serious that the US and South Korea may feel compelled to respond. Remco Breuker, Leiden Professor of Korean Studies, would like to see a European mediator.

The Dutch House of Representatives wants websites on which personal data is shared to be taken offline. Bart Schermer, an expert in privacy and cybercrime, commented on ‘RTL Nieuws’: ‘Providers who refuse to cooperate can be held liable.'

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

This article studies the securitization of immigration in the United States of America (U.S.), through the analysis of the National Security Strategies (NSS) published between 2002 and 2017, using a two-layered analytical framework that combines securitization theory and agenda setting theory.

At present, the cabinet still maintains that all provinces are motivated to cooperate with the sensitive issue of the nitrogen strategy. However, there are major concerns that the political landscape will look very different once the elections for the Provincial Councils on 15 March have been held.

Many Western defence strategies concentrate on maintaining the status quo. Actively promoting universal values can also be a good strategy for resilience, according to Theo Brinkel, Professor by Special Appointment in Military-Social Studies. Inaugural lecture 15 January.

LUGO and Campus The Hague employees will discuss sustainability in campus strategy. The university is discussing a new Development Strategy and Implementation Plan for Campus The Hague for the next decade (timeline: 2020-2030).

Bas Rietjens and his colleagues researched the Russia-Ukraine war, exploring this multitude of facets and their interconnections.

On Monday 28 September, the University Council (UR) will discuss the Development Strategy and the Implementation Plan for Leiden University's Campus The Hague 2020-2030. The plan will then be put on the agenda of the meeting of the UR with the Executive Board on 12 October. After this, the plans for…

This article written by Marieke Liem & Alexander Kamprad investigates the relationship between terrorism and interpersonal violence. They conducted cross-national analyses on the effects of terrorism mortality rates on homicide rates. Results showed that terrorism appears to be robustly and positively…

On the occasion of the launch of the Council of Europe’s new children’s rights strategy 2016-2021, the Republic of Bulgaria hosted a high-level conference in Sofia on the 5th and 6th of April, 2016.

Latent variable modeling of students' solution strategies and performance

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

The Social Domain Platform organized a regional meeting on homelessness on September 30 at the Pauluskerk in Rotterdam. At the invitation of Valente, the trade association for organizations that provide support to vulnerable people in our society, Martijn van den Brink was invited to speak about the…