1,282 search results for “efficient medicijnontwikkeling” in the Public website
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C5 (Clever Combination of Synthetic Compartmentalization, Carbon Fixation and Compound Biomanufacturing)
Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?
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Getting the electrons right for O2-on-metal systems
This thesis studies theoretical surface chemistry within the field of heterogeneous catalysis.
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High performance computing
A high performance computer or supercomputer owes its massive processing capacity to the fact that it chops a single overarching task into a whole series of smaller tasks. It simultaneously tackles each of those smaller problems.
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Deterministic equation solving over finite fields
Promotor: H.W. Lenstra
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mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
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Online Course Clinical Research Regulation in the Netherlands
Are you planning to conduct clinical research in the Netherlands? In this online course, you are introduced to legislation and procedures on clinical research in the Netherlands. It will help you prepare and submit your research file efficiently. The first three themes ‘The Dutch Review System’ , ‘The…
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Biomedical Microscale Analytics
The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…
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Learning Chairs
In the Department of Business Sciences, three chairs are established. Together, the chair holders lead the Turnaround, Rescue & Insolvency Leiden Research Team (TRI Leiden), which consists of legal and business science researchers from Leiden Law School. TRI Leiden aims, through an international and…
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Systems and Security
Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…
- Green roofs and Buildings
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The Metallophilic Interaction between Cyclometalated Complexes: Photobiological Applications
In this thesis, the researcher developed a nanosystem based on the metallophilic Interaction between cyclometalated complexes.
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Virtual Photography. Artificial Intelligence, In-game, and Extended Reality
While it has traditionally been seen as a means of documenting an external reality or expressing an internal feeling, photography is now capable of actualizing never-existed pasts and never-lived experiences.
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Team 6 Quality assurance in education
In order to successfully implement the kernvisie, it is important to examine how we can improve the quality of our education.
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Network and projects
Netwerk en projecten duurzaamheid verduurzaming green office en green team
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Large-scale Computing Infrastructure
Large-scale computing infrastructure, such as supercomputers, cluster, and clouds, are already pervasive, most members of our society interact with them daily: social networks, government services, media streaming services--all systems heavily interfacing with the members of our society--are powered…
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Spin transport and superconductivity in half-metallic nanowires and junctions
The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.
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LEAF
Leiden University encourages all its laboratories to obtain LEAF (Laboratory Efficiency Assessment Framework) accreditation.
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Electrolysis and fuel production
Electrolysis is a technique that can be used to convert CO2 into fuels and other useful products. To do this efficiently and on a large scale, however, we need to understand exactly how electrolysis works. Professor Marc Koper is an expert in this field.
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Redox catalysis for a sustainable energy infrastructure
The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…
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Study programme
The EG track is built on the foundation of MPA courses in which you gain understanding of the complexities of public institutions and acquire advanced academic skills. Specialisation courses focus on the welfare state, markets and competition, and political economy.
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Podcast series Computers don't byte
Leading computer scientists from a variety of fields share their expertise and insights. Dive into the minds of these researchers and learn about real-world applications, the future of AI and related technologies and cutting-edge research. From chatbots to cybersecurity, from quantum to children's stories,…
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Operando research in electrochemistry
The central theme of Rik Mom’s research group is to identify what the electrode-electrolyte interface looks like when electrocatalysis is taking place. Using specialized forms of Raman and X-ray spectroscopy, we study the chemical state and bonding environment of the electrode surface and near-surface…
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Polypept(o)ide-based nanostructures for therapeutic and diagnostic application
Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…
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Structured Parallel Programming for Monte Carlo Tree Search
The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.
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Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
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Conceptualising and developing the practice of CLIL teachers
How do teachers conceptualise, develop and implement an effective CLIL practice?
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Materials-GRoWL: Gauging the Rest-of-the-World’s Lifecycles of Construction Materials
What types of construction materials are used in the Global South, where are they, and what levels of societal services do they support? How will material use evolve under different development pathways and paradigms? What are these materials' environmental and societal impacts now and in the future,…
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Optimizing Solvers for Real-World Expensive Black-Box Optimization with Applications in Vehicle Design
PhD defence
- Science Coffee: Developing tools and practices to promote open and efficient science
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Parallel Worlds
In this PhD project, we focus on improving the effectiveness and efficiency of LMs with narrative data.
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Ultrasensitive in situ visualization of active glucocerebrosidase molecules
Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…
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Transcutaneous vaccination by means of coated and hollow microneedles
Transcutaneous vaccination is attractive because it is non- or minimally invasive, pain free and the site of administration (skin) is easily accessible. What’s more, transcutaneous immunization can lead to a strong immune response owing to the presence of immune-competent cells in the skin.
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Take your next step!
Together we can make science open. Find the next step that fits your journey here.
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Electroreduction of nitrate and carbon dioxide on copper electrodes: a mechanistic study
In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…
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Aspects of the analysis of cell imagery: from shape to understanding
In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.
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Learning to look at LiDAR: combining CNN-based object detection and GIS for archaeological prospection in remotely-sensed data
The manual analysis of remotely-sensed data is a widespread practice in local and regional scale archaeological research, as well as heritage management.
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The power of one qubit in quantum simulation algorithms
Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…
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Resource allocation in networks via coalitional games
Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone
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Print referencing during e-storybook reading on a SMART board for kindergartners to promote early literacy skills
This study examined the effects of a classroom-focused intervention on different domains of early literacy. The intervention consisted of shared e-book reading combined with a print referencing technique done via a SMART board. The specific goal of the study was to examine whether children could be…
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Interactive visual retrieval of academic literature
The available tools for academic literature search return a list of ranked documents, which might not be ideal for some tasks. To facilitate these tasks, I am creating a visual representation of the academic search space where the user can browse academic topics.
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Model-assisted robust optimization for continuous black-box problems
Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.
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Biotherapeutic Delivery
The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…
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Dynamic Nuclear Polarization agents
Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…
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Access to remediation
When companies violate women’s human rights.
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Selective electrochemical H2O2 production by a molecular copper catalyst: A crucial relation between reaction rate and mass transport
Hydrogen peroxide (H2O2) generation via electrochemical oxygen reduction is a sustainable production method for this bulk chemical. However, the selectivity of molecular catalysts for electrochemical H2O2 generation has hardly been investigated in a systematic manner, and it is unknown if their stability…
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On the optimization of imaging pipelines
In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…
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Copper complexes for bioinspired electrocatalysis relevant to the reduction of oxygen
This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.
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Feedback from deeply embedded low- and high-mass protostars. Surveying hot molecular gas with Herschel
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg
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Catalysis of the electrochemical water oxidation to oxygen
Promotor: M.T.M. Koper, Co-Promotor: F. Calle-Vallejo