Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

The key question addressed in this family study is whether the psychophysiological and neurocognitive abnormalities often reported in SAD patients are heritable and can thus be found in family members of SAD patients as well. Determination of heritability of these deficiencies is essential for endophenotyping.…

Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

The specialisation consists of 120 European Credit Transfer System (EC) points and includes courses and electives (30 - 60 EC) and and one or more research projects (60 - 90 EC).

This multidisciplinary minor addresses the fascinating question how we, modern humans, got to be the way we are. Who were our ancestors? How does our morphology, genetic makeup, brain and behaviour relate to that of other species? How does our evolutionary past affect our susceptibility to diseases?…

Do understudied animals contain hidden species?

Promotor: Prof.dr. J. Brouwer, Co-promotor: Dr. Remus Th. Dame

A novel in vivo model system for studies on glucocorticoid resistance

PhD defence

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

PhD defence

The organisation of the Platform for Postcolonial Readings is a collaboration of main organisers and occasional guest organisers.

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

A neurobiological perspective on individual differences in social competence

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Meet the ABPP2027 organizers

The research programme Probability Theory focuses on probability theory and on operations research.

Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!

Evolutionary and ecological interactions affect species on genetic and phenotypic levels. This theme aims to understand these processes at multiple levels: from molecules to genomes to populations and to communities. Our research focuses on evolutionary responses to anthropogenic change, the role of…

Institute of Political Science

The Faculty of Social and Behavioural Sciences (FSW) offers an inspiring and competitive, international working and learning environment to around 1,025 staff and around 7,000 students from home and abroad on 13 bachelor's, master's and research master's programmes.

A publication in Nature Plants by a team of Leiden biologists has received national and international media attention. The researchers can have annuals flower multiple times thanks to a particular gene they discovered.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

We investigate the processes underlying the patterns. We aim to explain biodiversity by investigating the distribution, function, development, and evolution of body forms, as well as physiological and behavioural variety among species. We collaborate with those specialized in describing, archiving,…

The programme group Learning and Behaviour Problems in Education is one of the six programme groups within the department of Child and Education Studies at Leiden University.

This study explores the role of linguistic data in the reconstruction of Dolgan (pre)history by analyzing contact-induced changes and using them to infer information about the nature of the contact settings in which they occurred.

Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…

Delineating psychophysiological endophenotypes of social anxiety disorder

LUXs unites statisticians from all over the university, who are all members of their own faculty. LUXs does not have its own organisational units, but it is coordinated by a Steering Committee.

The Institute of Education and Child Studies is part of the Faculty of Social and Behavioural Sciences at Leiden University. The institute is governed by an Institute Board under the direction of a rotating chairman, i.e. the Scientific Director and an Director of Studies. The Institute Board is…

The Executive Board and the Board of Education of the Institute of Psychology are responsible for the organisation. A number of committees offer specialised knowlegde, such as the Research Ethics Committee. Students have a say in programme committees.

The faculty has around 650 employees, academic and administrative staff. More than 325 of these are involved in teaching. Together they make Leiden Law School what it is today: a faculty driven by its research and enriched by its teaching.

The programme group Educational Sciences is one of the six programme groups within the Institute of Child and Education Studies at Leiden University.

The programme group Forensic Family and Youth Care Studies is one of the six programme groups within the department of Child and Education Studies at Leiden University.

Lecture, Comparative Indo-European Linguistics (CIEL) Seminars

The Mathematical Institute has a rather liberal management structure. Tasks and responsibilities are distributed among the staff. Important decisions are taken by consensus. Various organisational divisions are featured below.

The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).

A linguistic test of hypotheses rooted in genetics and archaeology.

To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.