Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…

On 10 november 2021, Carmel van Niekerk-Jacobs defended the thesis 'Realising the right to reproduce with assistance in South Africa'. The doctoral research was supervised by Prof. J.J. Sloth-Nielsen and Prof. T. Liefaard.

A new therapy for the serious Graft-versus-Host disease

Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.

Development & demonstration of low environmental impact innovation and optimization practices in pharma production.

It is a tragic fact that mass atrocities have been, and are being, committed across the world. The international community, while condemning these acts, often stands idly by. This conundrum raises a host of empirical, legal, and normative questions regarding the role of public opinion in responding…

This study documents and translates the Saa (Zapotec) cultural heritage of the Bene’ Ya’a/En’ne I’ya peoples, the Zapotec inhabitants of the Sierra Norte of Oaxaca.

From junior school pupils to university students: the Living Lab is a valuable place of study for many people. Every year the Living Lab trains dozens of students at vocational, college and university level. More than a thousand pupils also have lessons on location, and junior schools use over thirty…

Despite the value of technology integration for educational equity and quality being emphasized by numerous studies, many gaps exist about how technology integration can be approached in policy plans, implemented in pedagogical practices, and embraced by teachers, students, and parents.

Relevant safety issues are associated with hazardous materials transportation, especially when transport routes cross populated areas. This article for the Journal of Loss Prevention in the Process of Industries analyses a 2015 accident with a freight train in Tilburg, comparing it to the Viareggio…

An experimental approach to organic palaeolithic technology

The Private International Law Department provides academic education and performs research in the field of private international law.

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

On 25 May, Roxane de Massol de Rebetz defended the thesis 'Beyond the dichotomy between migrant smuggling and human trafficking: a Belgian case study on the governance of migrants in transit'. The doctoral research was supervised by Maartje van der Woude, Joanne van der Leun and Masja van Meeteren.

The focus of the dissertation

This dissertation provides a description of the phonology and morphology of Mambay, an Adamawa (Niger-Congo) language spoken by 15,000 people in Chad and Cameroon.

This project focuses on the study of Neanderthal and early modern human behavior, primarily on the basis of stone tools, fauna and spatial patterns

In 1940 the Germany occupiers ordered the dismissal of all Jewish staff of the university. This resulted in protest speeches by fellow academics.

This book analyses the expulsion of delinquent foreigners and their exclusion from the territory through a comparative lens.

Reading emotions from others’ faces strengthens social relationships. But how is that for children with hearing loss? Can they learn to read faces just as easily as hearing children? The study by Yung-Ting Tsou and colleagues shows that daily

This book explores the fascinating microvariation in Bantu languages and proposes a new syntactic analysis of subject and object agreement crosslinguistically. This book is open access!

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In order to analyze the challenges linked to data use in the context of nexus governance, Giest & Mukherjee use a policy design lens and more specifically the perspective of organizational policy instruments to look at the Mediterranean region.

How might viola and string quartet playing in the performer-centered, moment-to-moment and communicative style heard on early recordings be brought about today?

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

La naissance d’une thalassocratie considers the contribution of the Burgundian and Habsburg Netherlands to the rise of the Dutch Republic as a maritime power. In Braudelian fashion, its chapters follow three lines of research.

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

If you wish to know exactly what is going on in a healthy or sick human body, and at various levels such as molecule, cell, tissue, organ, larger systems and a person as a whole? Do you wish to learn how to do research which contributes to diagnoses, treatment and prevention of diseases? Then the bachelor…

This dissertation presents a grammar of Khwarshi, a Nakh-Daghestanian language.

The chaotic years after the Civil War are often seen as a time of uniquely American idealism—a revolutionary attempt to rebuild the nation that paved the way for the civil rights movement of the twentieth century. But Adam Fairclough rejects this prevailing view, challenging prominent historians such…

This study presents a full descriptive account of the grammar of Mualang, covering the major features of phonology and morphosyntax as well as issues related to pragmatics.

Muslim scholars work in a long and rich tradition of knowledge-production in their own culture.

Promotor: P.D. Grünwald

Promotor: Prof.dr. R. Verpoorte, , Co-Promotor: Young Hae Choi

This thesis investigates the processing of words written in Japanese kanji and Chinese hànzì, i.e. logographic scripts.

This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

On 17 December 2018, Dejian Kong defended his thesis 'Civil Liability for Damage caused by Global Navigation Satellite System'. The doctoral research was supervised by Prof. dr. P.M.J. Mendes de Leon.

This article aims to provide a coherent foundation for empirical studies of interpersonal discussion on risk.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Discover why Leiden University is the ideal place for the MSc Dutch Politics: a broad political science department, expert faculty, small-group teaching, and a vibrant student city.