In the International Studies programme, you will develop both the knowledge and the critical insight needed to gain regional expertise within a global context. In addition, you will acquire the practical and professional skills that will help you in making your first steps in your career, whether you…

The Hans Franken Lecture honors the legacy of Prof. Dr. Mr. Hans Franken, a founding figure of eLaw in 1985.

The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…

Key publications of the Predictive Pharmacology group.

CWTS is proud to announce its new research programme for the period 2017-2022.

As an R&D manager, how can you measure the R&D (research and development) performance of your firm? How does knowing the importance of different R&D measures allow R&D managers to formulate more effective strategies to improve their firm’s R&D performance?

Leiden University and the city of The Hague are working closely together to increase the impact of our research and education in order to contribute as much as possible to the development of the city.

What mechanisms shape faculty members' perspectives on their teaching role in research intensive universities?

A new research line is the development of liquid biopsy fingerprints to predict early Alzheimer’s disease (AD) stage in human in readily accessible body fluids in human (in collaboration with: Dr. Geert-Jan Groeneveld, CHDR; Prof. Elga de Vries, Free University Medical Center; and others).

Globalisation is shaping the world in which we live. In the BA in International Studies, you have the opportunity to study one of eight world regions within the context of global interactions. At the same time, you will learn a key language of your chosen region and acquire skills that will prove to…

During this programme you will acquire in-depth knowledge of one of eight world regions by studying its politics, economy, history and culture, and a local language. You will gain the ability to place regional developments in a global context, providing a strong preparation for the labour market in…

Are the types of school non-attendance which have been evidenced in typically developing youth also found among children and adolescents with an intellectual disability (ID)? If so, which types are most prevalent and thus in greatest need of attention, and what factors (child, family, school/environmental)…

Using biomethane to produce ammonia, a crucial chemical in agriculture, could drastically reduce the climate impact of the process. In a study published in One Earth, researcher Robert Istrate shows it’s even possible to make ammonia production net-zero or carbon negative.

The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

In this thesis, topics relating to the optimization of high-throughput pipelines used for imaging are discussed. In particular, different levels of implementation, i.e., conceptual, software, and hardware, are discussed and the thesis outlines how advances on each level need to be made to make gains…

An overview of research themes and projects at ABS.

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Every month a member of the Institute for History tells about a book that inspired him or her. Afterwards, the pen is passed on to another colleague. This month dr. Meike de Goede tells about the book 'Between Tides' by Valentin Mudimbe. The novel, little known beyond the circles of Africanists and…

Assessing and implementing new diagnostics strategies for stratifying patients

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Promotor: Prof.dr. T. Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

Quantum computing is a novel paradigm for computation, which is nearing real-world impact with the coming generation of limited, but nonetheless powerful quantum devices.

Experience a different university, and a different perspective, through the Live My Life programme.

How did digital intermediality symbolise and facilitate the transfer of content from popular culture into policy statements and vice versa in the period between 1945 and the new millenium?

What is the provenance of introduced populations?

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Grants awarded to molecular physiology research

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

How to stimulate novel research in science and innovation

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Maurijn van der Zee searches for insecticides that protect crops without harming wildlife or leaving residues in our food. His GREENSHIELD project received funding from the NWO Open Technology Programme.

Can small molecule drugs restore the immune system’s ability to fight tuberculosis by boosting autophagy?

Every time we pay for something, our money moves through global technical systems that connect the world economy. These systems are convenient, but they also expose users to Western sanctions, prompting countries like Russia to look for alternative financial infrastructure.

Terms used by literary critics in characterizing the style of novels are often impressionistic (‘baroque’, ‘austere’, ‘vivid’, ‘cerebral’ etc.). Foundations for such evaluations are usually not provided. A scientific way of studying and explaining style is lacking in present day Dutch Studies. Suzanne…

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Decision support tool for cell therapy commercialization and business development