The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Training a robot in a real-life environment is more or less impossible. Computer scientist and psychologist Roy de Kleijn switched to training in a simulated, virtual one instead. ‘You do have a reality gap, but the more precisely you train the robot, the better it is in practice.’ His inspiration:…

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars (exoplanets). They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems. This way they address…

Researchers at Leiden Observatory study the fundamental physics that creates structure in the Universe. These processes collect matter into galaxies and gas into stars. With the use of powerful telescopes and advanced calculations and computer simulations, Leiden astronomers seek to understand the origin,…

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

Modern society is connected through electronic and mobile devices, which we call the Internet of Things (IoT).

This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.

Astronomers want to understand the Universe, from the Big Bang to the present day, and what the future will hold. In Leiden they focus on two key questions: ‘How did stars and planets originate’ and ‘How were galaxies and black holes formed in the young Universe?’ A new generation of telescopes – just…

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Digital Archaeology is concerned with digital data for for archaeological research, and the computational methods and tools required to collect, analyse and manage it.

Researchers at Leiden Observatory study the fundamental physics that creates structure in the Universe. These processes collect matter into galaxies and gas into stars. With the use of powerful telescopes and advanced calculations and computer simulations, Leiden astronomers seek to understand the origin,…

Our project focuses on the analysis of decision-making processes in the European Union (EU) and explores how approaches and tools to understand decision-making found in both the Natural and the Social Sciences can be linked, knowledge between these traditions exchanged and synergies utilized. To explore…

Source: Mol Pharmacol, Volume 87, Issue 2, pp. 305-13 (2015)

Supervisor: Gerard van Westen

Born in Europe roughly 100 years ago, quantum physics brought forth a veritable technological revolution through semiconductors, lasers, fibre optics, and many other technologies that are today ubiquitous in our lives. Now, during the second quantum revolution, Europe can take the lead once more in…

The following master research projects are currently open in the Bouwmeester group.

‘I would never want to be treated by a computer,’ says Boudewijn Lelieveldt, Head of Radiology at the Laboratory for Clinical and Experimental Image Processing and Medical Delta professor in the Bioinformatics group at Delft University of Technology. No matter how intelligent a system, we have to continue…

In this thesis, we investigate how deep generative models (AI models that can create new designs) can be better utilized for technical and industrial design. Our goal is to generate designs that are not only realistic (plausible), but also efficient, reliable, and usable in complex 2D and 3D applica…

Within the two-year Astronomy master’s programme, you can choose from seven specialisations, ranging from fundamental or applied astronomy research in cosmology, instrumentation or data science, to combinations of astronomy research with education, management or science communication.

Research at Leiden Observatory spans the full width of modern astrophysical enquiry. It is based on observation, theory, simulation, and experiment. Two broad clusters characterize the ongoing research. Within each theme, researchers carry out their personal and specialized research programme. The two…

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

Mathematical models of software systems enable characterizations, abstractions, simulations, and analysis of complex software during its development.

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The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

Making systems biology modelling a central pillar of research in biology

In what way can the qualities of an existing context be used as guiding and enriching principles rather than limiting factors in the process of spatial transformation?

Computer applications and quantitative methods in archaeology CAA95.

In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.

This thesis introduces the concept of

The group Theoretical Physics of Life Processes, led by Helmut Schiessel, focuses on the physics of chromatin, the DNA-protein complex that fills the nuclei of eukaryotic cells.

A modeling approach with applications to the Bau de l'Aubesier (Southeastern France)

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

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Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Forming at the nodes of the Cosmic Web and growing hierarchically via mass accretion, galaxy clusters are the largest virialized halos in our universe, composed of dark matter (DM; ≥85%), ionized hot plasma in the intracluster medium (ICM; ≥10-15%), and galaxies (≥1-5%).

Neo-Baroque construction and deconstruction of the concepts of paradise in fiction.

Exploring the integration of AI and quantum computing, this study adapts Knowledge Representation and Reasoning (KRR) to enhance quantum circuit simulation and optimization.

The focus of our theoretical research is understanding the behaviour of soft condensed matter, physical matter which is deformed or structurally altered by thermal fluctuations or small stresses.

PhD Research Projects at LUCDH and Affiliated Faculties