Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Parasitic worms and stomach bacteria suppress immune reactions such as allergic responses. Parasitologist Hermelijn Smits and lung specialist Christian Taube from the LUMC are trying to learn from these micro-organisms.

There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.

How are the epidermal lipid pathways involved in health and disease.

Wenxin Wang defended her thesis on 26 October 2016

Overview of the Leiden Asia staff per area or country.

D.P. Kok defended his thesis on 10 October 2017

Key publications of the Aging and Immunity group

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

How can collaborative participatory action research by student-teachers and their students enhance student participation, improve educational practices, and generate knowledge about these practices that can be used for improving teacher education as well?

Education and Organisation Development

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

On 7 September 2023 Didem Durak Akser successfully defended a doctoral thesis and graduated.

On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.

Artful Mathematics: The Heritage of M. C. Escher

Saeedeh Shahnahpur defended her thesis on 13 September 2016.

On the 15th of July Sawako Takemura successfully defended a doctoral thesis and graduated.

On 30 January 2024 Jurre van der Meer successfully defended a doctoral thesis and graduated.

The staff members of the Methodology & Statistics unit are members of various boards and committees.

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

A starring role for PhD candidate Andreea Nadaban during the annual meeting of the European Epidermal Barrier Research Network. With her talk about the arrangement of lipid molecules in the upper layer of our skin, she won the award for Best Oral Presentation.

One of the ways of understanding another culture better is to examine what people experience when they read a text, or look at an image. Leiden experts have a lot of knowledge in this field, for example on culture in ancient Japan.

On 1 September 2022 Afke van Ewijk successfully defended a doctoral thesis and graduated.

On 18 October 2022 ms. Comstock-Skipp successfully defended a doctoral thesis and graduated.

This project aims to situate the current policy concept of ‘valorization of scientific knowledge’ in historical and epistemological perspectives. Conceptual understanding of the utility of scientific practices is developed in dialogue with historical analyses of the politics of knowledge in European…

Policy studies and interventions in the field of Youth

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

The LUCDH foster the development of new digital research by awarding a number of Small Grants each year. As in previous years the LUCDH received a large number of excellent grant applications for Research and Personal Development funds. Congratulations to the recipients of this year's research award…

Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit

Tineke Berkers has won an award for outstanding contribution for her poster at the Gordon Research Conference at Waterville Valley, USA.

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.

In this article, Friso Selten and Bram Klievink explore how public organisations strategically manage the adoption of AI.

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.

Peak Performance: Collaborative Crisis Management Before and During International Summits. This comparative case study probes into conditions for collaborative governance in the security organisation of international summits.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

PhD defence

PhD defence