What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

How are the epidermal lipid pathways involved in health and disease.

There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

‘Regenerative medicine’ explores ways to repair or replace damaged cells, tissues and organs with cell, stem-cell or gene therapy. It can lead to valuable breakthroughs in the treatment of chronic diseases such as diabetes, heart problems and kidney diseases or muscle diseases.

Parasitic worms and stomach bacteria suppress immune reactions such as allergic responses. Parasitologist Hermelijn Smits and lung specialist Christian Taube from the LUMC are trying to learn from these micro-organisms.

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Key publications of the Aging and Immunity group

Overview of the Leiden Asia staff per area or country.

Wenxin Wang defended her thesis on 26 October 2016

D.P. Kok defended his thesis on 10 October 2017

How can collaborative participatory action research by student-teachers and their students enhance student participation, improve educational practices, and generate knowledge about these practices that can be used for improving teacher education as well?

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

The staff members of the Methodology & Statistics unit are members of various boards and committees.

On the 15th of July Sawako Takemura successfully defended a doctoral thesis and graduated.

On 7 September 2023 Didem Durak Akser successfully defended a doctoral thesis and graduated.

Artful Mathematics: The Heritage of M. C. Escher

On 30 January 2024 Jurre van der Meer successfully defended a doctoral thesis and graduated.

On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.

Saeedeh Shahnahpur defended her thesis on 13 September 2016.

On Wednesday 3 September 2025 Yu Ai successfully defended a doctoral thesis and graduated.

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

A starring role for PhD candidate Andreea Nadaban during the annual meeting of the European Epidermal Barrier Research Network. With her talk about the arrangement of lipid molecules in the upper layer of our skin, she won the award for Best Oral Presentation.

One of the ways of understanding another culture better is to examine what people experience when they read a text, or look at an image. Leiden experts have a lot of knowledge in this field, for example on culture in ancient Japan.

On 9 October, Corné Smit defended his doctoral thesis, 'Minority governments in the Netherlands and Denmark '. The PhD research was supervised by Luc Verheij and Geerten Boogaard.

Tineke Berkers has won an award for outstanding contribution for her poster at the Gordon Research Conference at Waterville Valley, USA.

On 1 September 2022 Afke van Ewijk successfully defended a doctoral thesis and graduated.

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

This project aims to situate the current policy concept of ‘valorization of scientific knowledge’ in historical and epistemological perspectives. Conceptual understanding of the utility of scientific practices is developed in dialogue with historical analyses of the politics of knowledge in European…

The Move-In Days will take place on 15-16 August 2026. In order to prepare yourself for your Move-In Day, we want to share with you some more info, and what to expect before this date. DUWO - our student housing partner that deals with LUC's housing will be in touch with you in the summer to start…

Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

In this article, Friso Selten and Bram Klievink explore how public organisations strategically manage the adoption of AI.

This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Peak Performance: Collaborative Crisis Management Before and During International Summits. This comparative case study probes into conditions for collaborative governance in the security organisation of international summits.

With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.

This 48-month project is to contribute to a solid, accessible, domestically owned knowledge base for people-centred interventions aimed at strengthening access to justice in Libya (A2JiL), and to disseminate such knowledge among stakeholders, enhancing awareness and the capabilities required to provide…