925 search results for “biological check” in the Public website
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Topological decoding of biomolecular fold complexity
Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…
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Anisotropy in cell mechanics
Mechanical interactions between cells and their environment play an important role in many biological processes.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
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Human skin equivalent barrier optimization
The currently available in vitro generated human skin equivalents resemble the human skin in many aspects. However, some essential barrier characteristics do not fully mimic the native barrier. Consequently, the human skin equivalents cannot be used for screening of drugs for skin penetration.
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Quantifying nucleosome dynamicsand protein binding with PIE-FCCS and spFRET
In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…
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Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays
In the literature, several types of microneedles have been extensively described. However, porous microneedle arrays only received minimal attention. Hence, only little is known about drug delivery via these microneedles. However, porous microneedle arrays may have potential for future microneedle-based…
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Flow Cytometry Core Facility
The LUMC Flow Cytometry Core Facility accommodates all research and diagnostic flow cytometry equipment of the LUMC.
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Two-photon luminescence of gold nanorods: applications to single-particle tracking and spectroscopy
Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.
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Immunotherapy to limit atherosclerosis-projects
For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.
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Potentiation of Gram-positive specific antibiotics against Gram-negative bacteria through outer membrane disruption
Extending our current arsenal of antibiotics is key to staying ahead in the arms race between humans and resistant bacteria.
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SCALES project
How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?
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Why Leiden University?
The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Chemistry. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either Chemical Biology or Energy & Sustainability. During the Master's…
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More efficient learning thanks to sleep
Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.
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Chimpanzees recognise one another from their rear ends
It is important for social animals to be able to recognise one another quickly. Humans are able to recognise each other immediately from their faces. Faces are also important for chimpanzees, but a new study by neuropsychologist Mariska Kret in PLOS ONE shows that the animals' buttocks also play a…
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Research Themes
Members of the collective explore what it means to be ‘human’, in the past and present, from a range of different perspectives and inter-disciplinary approaches.
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Research with animals
At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Fires, Food and the Evolution of Human Detoxification Capabilities
A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…
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Protein condensates as Materials
We have recently discovered that there are biological proteins that phase separate out of solution much the way oil will de-mix from water (see movie). These form dense, liquid-like phases called protein condensates.
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Theoretical Physics
In the spirit of 'unity in diversity', our objective is to promote insight into and appreciation for the wonder that the same physical laws and mathematical concepts apply to the whole of nature, from the largest to the smallest energy and length scales. We strive for the application of abstract theoretical…
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Flagships
In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.
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Bright Horizons: Adjunctive Light Therapy for PTSD
Exploring the synergy of light therapy and exposure psychotherapy to enhance PTSD treatment outcomes.
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Sourav RoyFaculty of Science
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Guiju Duan
Faculty of Science
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Silvana Caipa CureFaculty of Science
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Tuo Maidina
Faculty of Science
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Meg FergusonFaculty of Science
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Parisa Omidvar
Faculty of Science
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Jingjing Wang
Faculty of Science
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Alexandre MorinFaculty of Science
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Yunhao DuanFaculty of Science
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Paul Baconnier
Faculty of Science
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Colin MeulblokFaculty of Science
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Sander Kammeraat
Faculty of Science
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Gert-Jan Kuijntjes
Faculty of Science
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Tommaso Gili
Faculty of Science
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Jeremy ErnstFaculty of Science
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Donny de Bruin
Faculty of Science
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Martina HuberFaculty of Science
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Yvonne Kerkhof
Faculty of Science
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Connie van Gent-van DorpFaculty of Science
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Edgar GroenenFaculty of Science
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Wim van SaarloosFaculty of Science
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John van NoortFaculty of Science
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Margot TeunisseFaculty of Science
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Peter GastFaculty of Science
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Alessio Catanzaro
Faculty of Science
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Francesca GiuffridaFaculty of Science