The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.

Speech Prosody is the biennial meeting of the Speech Prosody Special Interest Group (SProSIG) of the International Speech Communication Association (ISCA).

SBB research focuses on the complex operational, organisational dynamics of technology-intensive sectors.

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

Publications from the Project 0100 team members.

This dissertation was to develop effective graphene-based nanofluidic devices by developing scalable fabrication methods and elucidating proton transport mechanisms.

The comprehensive bachelor’s and master’s programmes at the Leiden University Centre for Linguistics (LUCL) train students to become fully-fledged LLM engineers and analysts – with a foundation in linguistics!

PhD defence

To be eligible for Creative Intelligence & Technology (previously Media Technology) at Leiden University, you must meet the following admission requirements.

As environmental and ecological changes and their impact become more urgent, demand for Industrial Ecology experts is rising. More and more national and international companies, local and national governments and NGOs are interested in our alumni, who possess the interdisciplinary perspective and skill…

Intelligent machines are going to make ethical decisions too. Should a self-driving car be allowed to slam into pedestrians to save its passengers from a head-on collision? Should a negotiation app be able to detect stress in your opponent’s voice? And who makes these decisions: the user, the system’s…

Contemporary societies experience numerous crises, risks and disasters. In this minor, you will explore each of these themes in relation to grand challenges such as climate change, intensified disasters, cybersecurity incidents, and risks associated with emerging technologies.

This is an Erasmus+ International Credit Mobility project of the Faculty of Science with three universities in Colombia.

This PhD project investigates how language models can be used to extract structured knowledge from text in a way that is accurate, robust, and applicable to real-world use cases.

Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.

Research in the Natural Computing and Optimization cluster covers theoretical foundations, the development of new algorithms, and interdisciplinary applications of natural computing methods.

How do protein modifications work together to repair DNA, and what can we learn about these interactions to better understand disease?

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.

We will use Artificial Intelligence to make an intelligent, multilingual search engine for archaeological texts, which will enable new discoveries about the human past.

Through our research, we aim to enhance both scholarly understanding and practical knowledge in sustainability governance, while making meaningful contributions to the public debates on these critical issues. To achieve this goal, we embrace diversity in our research topics, methodological approaches,…

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

The Leiden Institute of Advanced Computer Science (LIACS) of Leiden University proudly establishes the Blaise Pascal chair. The chair applies for one year and is meant to strengthen the cooperation of the Leiden computer science research with foreign institutes.

Our education specializes in creative exploration and a broad understanding of scientific research and technology. It prepares students for a career involving creative and critical thinking, and in particular for a future in scientific research.

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

Promotor: Prof.dr. J.N. Kok, Co-promotor: Dr. A.J. Knobbe

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

Promotores: F.H. van Lunteren, F.P. Israel

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

This book focuses on policing in city-regions in Europe bringing together experts from across the continent to develop a sociology of urban policing and a unique methodology for comparing different metropolises in the same country.

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

Statistical considerations guide the design and implementation of the experiments that scientists perform. For instance, in a clinical trial about a the efficacy of a treatment, its effect in a certain minimum amount of patients has to be observed in order to make confident assertions about the efficacy…

Advanced biotechnology allows us to select or alter the genetic makeup of human embryos. What limits do we impose on biotechnological intervention in nature and the human body? And whose call is that?

List of Support Departments at LION and the Faculty of Science

Paul Hudson, Associate Professor of Physical Geography at Leiden University College, examines human impacts on lowland rivers in his new book.

Sport Data Center

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

In contemporary India, the regional state of West Bengal has often been perceived as somewhat of an aberration in the wider context of a rather chaotic democracy, as the Left Front (spearheaded by the Communist Party of India-Marxist, CPIM) demonstrated a rare instance of political stability, decisively…

Leiden University has developed a radically different method for large scale production of diverse nanoparticles and their alloys.

Many internal and external parties are involved in the expansion of the Gorlaeus Building.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

With an ever-increasing amount of data generated worldwide, industry, governments and academia highly welcome professionals with specific knowledge and skills to handle big data.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

LUdev is a student-run company within the Leiden Institute of Advanced Computer Science (LIACS). We are responsible for acquiring real-world software development projects, giving bachelor’s students the opportunity to apply the technical and theoretical knowledge gained during their studies in a professional…