1,282 search results for “efficient medicijnontwikkeling” in the Public website
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Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
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Westerdijk parking garage
Westerdijkgarage, Johanna Westerdijkpad 12, 2342DJ, Oegstgeest
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Programme structure
Through courses and research projects, you are trained by experts in the field.
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Programme structure
The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.
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Efficient Tuning of Automated Machine Learning Pipelines
PhD defence
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Jaap VisserFaculty of Science
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Deekshitha DeekshithaFaculty of Science
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Yuxuan ZhaoFaculty of Science
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Weikang WengFaculty of Science
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Research
Research in the POD-group addresses all features of random phenomena – modelling, structuring, analysis, control, optimisation – and covers both fundamental and applied aspects.
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Theory
Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…
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Leiden University is making the switch too
We are doing all we can to save energy at the university. Find out how you as a member of staff or student can do about energy and help reduce CO2 emissions.
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Research
An overview of the research at the Biologics Formulation group
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Fundamental Research in Energy & Sustainability
Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this population will result in an enormous increase in the demand for food, consumables, water…
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Probability theory
The research programme Probability Theory focuses on probability theory and on operations research.
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LIFE-GREENAPI
Development & demonstration of low environmental impact innovation and optimization practices in pharma production.
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Microbial enzymes for degradation and upcycling of natural and non-natural polymers
Learning from nature and utilizing microbial biodiversity to identify and characterize enzymes for degradation and upcycling of plastics and other polymeric materials.
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Joost Batenburg about AI Leiden style: 3D images and ensuring AI belongs to everyone
Joost Batenburg is a mathematician and computer scientist who works to build bridges to other disciplines. He hopes to bring intelligent software to fields where it can make a difference. Conversely, he also seeks connections to the disciplines that are needed to make AI a success.
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Research
Research at the Catalysis and Surface Chemistry group is comprised of the following research themes:
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Partnerships
The LACDR represents the core of bio-pharmaceutical research at Leiden University, and we interact closely with our partners:
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Large scale visual search
Promotor: J.N. Kok, Co-promotor: M.S. Lew
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Unconditionally secure cryptographic protocols from coding-theoretic primitives
This dissertation presents new cryptographic protocols, which can be divided into two families.
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Ehrenfest parking garage
Ehrenfestgarage, Emmy Noetherweg , 2333BK, Leiden
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Residential Concept
Living together in a residential setting adds another dimension to this learning, as our students have to learn to live with others who may not share the same daily routines or standards.
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Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
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Photon detection at subwavelength scales
Promotor: E.R. Eliel, Co-Promotor: M.J.A. de Dood
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Constraint-Based Analysis of Business Process Models
Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.
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Film Studio
The Film Studio in Huizinga 0.13 has facilities to record professional videos for a range of educational and/or research purposes.
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Mutual intelligibility of Chinese dialects: an experimental approach
This study examines the mutual intelligibility between all 225 pairs of 15 Chinese dialects, in two main branches, i.e., six Mandarin dialects and nine non-Mandarin (Southern) dialects.
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Unraveling modular architecture and domain engineering of carbohydrate-active enzymes: key insights for sustainable bio-based processes
This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…
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Unraveling the auxin mechanism in 2,4-D induced somatic embryogenesis in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Photoinduced processes in dye-sensitized photoanodes under the spotlight: a multiscale in silico investigation
With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…
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The social ties that bind: the role of social relations and trust in EU intelligence cooperation
Intelligence scholars have been struggling to find the conditions under which international intelligence cooperation occurs. Most focus on transactional motives and guaranteed returns, the so called ‘Quid pro Quo’. At the same time, trust is often mentioned as one of the foremost conditions, yet it…
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists
Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)
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Smart Courts, Smart Justice? Automation and Digitisation of Courts in China
On Tuesday 3 September 2024 Straton Papagianneas successfully defended a doctoral thesis and graduated.
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Energy Survival Guide
This book provides the answers, presenting clear insights into the current state of affairs and exploring future prospects.
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Does feedback targeting text comprehension trigger the use of reading strategies or changes in readers' attitudes? A meta-analysis
Our previous meta-analysis (Swart et al., 2019) had shown that feedback targeting text comprehension given when students perform a reading task positively influences learning from text. So far, differences in the effects of feedback were explained by design features, such as the timing and richness…
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When galaxy clusters collide: the impact of merger shocks on cluster gas and galaxy evolution
Promotor: Prof.dr. H.J.A. Rottgering, Co-promotor: David Sobral
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On a quest to discover where stellar-mass black holes merge: testing the AGN binary formation channel with spatial correlation analyses
The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.
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Zebrafish Delivery
Is there a sufficiently large market for drug screening and testing in Zebrafish larvae using membrane fusion?
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Key publications
Key publications of the Biologics Formulation group
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Membrane Interactions
Membrane proteins and membrane interactions of proteins are studied by spin label EPR. Intact, native membranes, vesicles of all sizes and nano-disks can be investigated, because the size of the object does not matter in EPR. Whereas solution NMR is limited to micelles (a few nm in diameter), by EPR…
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp