Visualising structures of life

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.

The Biological- and Soft-Matter Physics Master specialisation is one of the two programmes Leiden offers in experimental Physics. The programme can to a high degree be tailored to individual needs and interests.

Research at the THEOR group is comprised of the following research themes:

We aim to provide new insights relating to the spectacular multi-cellular life cycle of streptomycetes and other actinobacteria.

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

Steffen Brünle's group investigates G protein-coupled receptors (GPCRs). These essential membrane proteins are prime targets for therapeutic drug development in disease and cancer treatment.

X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.

With textnets it is possible to visualize and analyze textual data in novel ways.

How do bacteria sense and adapt to their environment? Ariane Briegel, Professor of Ultrastructural Biology, is intrigued by this question. Using new techniques, she produces three-dimensional images of bacteria that provide us with new clues about their sensory system.

Research at the MCBIM group is comprised of the following research themes:

Bachelor projects are available in

In the Aarts lab we combine or structure materials, mostly in thin film form, in such a way that the hybrid has different and novel properties or functionalities.

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An international team with researchers from Leiden revealed how a bacterium repurposed an internal system to control its movements. Movement control is very important in host invasion, which can lead to disease. Publication on 27 April in Nature Communications.

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

This thesis focuses on the concepts of freedo and fixity as two central topics of my artistic research. I present, analyze. and contextualize four of my works which have explicit links to fleedom and fixify and which demonstrate the dynamic interrelationship between the two.

X-Ray Diffraction (XRD), Nuclear Magnetic Resonance (NMR) and Cryo-electron microscopy (Cryo-EM) are the three main methods for solving structures of macromolecules.

Dynamic nuclear polarization with paramagnetic agents can enhance nuclear magnetic resonance signals by orders of magnitude. The mechanism of enhancement depends a.o. on the magnetic resonance properties of the agents used. Electron spin relaxation times at NMR relevant magnetic field/microwave frequencies,…

The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.

Louk Rademaker is visiting fellow at Leiden University, Lorentz Institute for Theoretical Physics. He studies theoretical quantum matter physics, connecting the material science to fundamental concepts and methods.

This dissertation was to develop effective graphene-based nanofluidic devices by developing scalable fabrication methods and elucidating proton transport mechanisms.

The focus of Jan Zaanen's theoretical physics research was the nature of macroscopic matter that is in one or the other way still in the grip of quantum physics.

Nonadiabatic energy transfer from the translational motion (T) of a molecule impinging on metal surface to the metal’s electrons may determine whether the molecule can lose enough energy to adsorb or react.

This book is the first systematic analysis of the changes in the use of goods and services by households of Black South Africans since the early nineteenth century.

This is the physics summer school of Leiden University. It is part of the Leiden Institute of Physics (LION). The summer school is intended for Bachelor (BSc) students in physics. It covers topics from quantum matter and optics, to biological & soft matter physics and cosmology and theoretical physics.…

As part of LUGO’s focus on responsible recycling of e-waste (electronic waste) we participated in the Funky Phone Challenge.

The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…

Special amplifying agents can make MRI scanners and NMR techniques hundreds of times more sensitive. Leiden physicists have now found a method to test their efficiency. More sensitive MRI scans could for example improve our understanding of cystic fibrosis or Parkinson’s disease. Publication in PCCP…

Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…

A full overview of MacBio PhD Theses.

The Academy of Creative and Performing Arts (ACPA) provides artistic research and education in the arts.

By detecting the tiny forces between a micrometer sized magnet and the spins of hydrogen nuclei, we can do MRI with a volume resolution that is approximately 12 orders of magnitude better than a conventional MRI.  

Research at the Catalysis and Surface Chemistry group is comprised of the following research themes:

LACDR adheres to strict data management rules, with the aim to make our data findable, accessible, interoperable and re-usable. For this reason all LACDR PhD candidates are required to prepare a data management plan and to implement data management rules accordingly. All PhD candidates follow a data…

PhD defence

Archaeometric analysis of glazed pottery assemblages from the Early Byzantine to the Early Modern periods in the Aegean.

Research at the BPOC/SSNMR group is comprised of the following research themes:

Humanity stands at a pivotal juncture, facing the dual challenge of environmental sustainability and rapid population growth, projected to exceed 11 billion by century’s end.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

The HJD Article Award is a biannual award given to the published research article which best advances the theoretical and/or empirical study of diplomacy.

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…

Develop EPR instrumentation and methodology to investigate intrinsically disordered proteins (IDPs).

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

Developing new methods for performing improvised music