Lions in Kenya respond very differently to human land use, climate and conservation practices. That is the conclusion of thesis from Leiden biologist Monica Chege. A uniform approach is therefore insufficient. ‘Effective conservation only works when management is tailored to local conditions and developed…

All acute care staff at Leiden University Medical Center have received their first and sometimes even their second dose of the coronavirus vaccine. But how long will you be protected after vaccination and what does the genetic material of the virus do in the vaccine? Our virologists Ann Vossen and Leo…

Eleven researchers from Leiden University have been awarded an Open Competition Domain Science ENW XS grant by the Dutch Research Council for their research projects. They are researching how to make software faster and greener, improve cancer detection and reduce anxiety by manipulating the biological…

Everything biobased: Plastic, medicine and fuel. It seems like a futuristic utopia. But for how long? A collaboration of researchers now proposes an idea to accelerate the development process. By combining machine learning and laboratory automation, this biobased ideal may become a reality rather sooner…

In this episode we talk with Mara van der Meulen about prosocial behaviour and social exclusion in children. Van der Meulen also explores the role of genetics and environment in the development of social behaviour. To find out more about her research on why some children are beter able to develop their…

PhD defence

EUFEPS Women in Pharmaceutical Sciences Award for Jara Bouma

LIACS scholars Thomas Bäck and Hao Wang will be the new Editors-in-Chief of the Evolutionary Computation Journal from November 1. Published by MIT Press since its foundation in 1993, the journal stands as a keystone in the field, providing a global platform for researchers exploring the workings of…

The genetic material of currently living Europeans is partly of Neandertal origin. Were our ancestors successful because they were hybridising and interacting with the local populations they encountered when migrating into new places? This subject takes centre stage in a beautiful documentary produced…

From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…

A major new study of ancient DNA has traced the movement of people into southern Britain during the Bronze Age. In the largest such analysis published to date, scientists examined the DNA of nearly 800 ancient individuals. Publication in Nature on December 22, 2021.

SAILS and CAIRELab, the LUMC’s AI expertise centre, recently held an event that gave healthcare professionals and computer scientists the chance to meet. The meeting proved fertile ground for new collaborations.

When a baby is born too soon, every minute counts – and so does every decision. To reduce uncertainty in those critical moments, biopharmaceutical scientist Manchu Umarani Thangavelu dedicated her PhD to identifying molecular markers of preterm birth and neonatal infection.

Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

Tuberculosis bacteria survive by hiding in our immune cells. In her PhD research, biologist Salomé Muñoz Sánchez explores how boosting the body’s own defenses might outsmart this deadly pathogen. Her work reveals two key proteins that help immune cells destroy the bacteria.

The Board of Governors is pleased to announce that Professor Cisca Wijmenga has been appointed by outgoing Minister of Education, Culture and Science Robbert Dijkgraaf as its new member.

RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.

There seem to be genes that influence how our brains develop over time. A large international consortium has discovered this with an extensive study. The results of the study were recently published in Nature Neuroscience.

Leiden's iGEM team has won high honours at the Grand Jamboree in Paris. The biology students came second in the Overgraduate category with their project PHAse Out. They also took home awards for Best Biomanufacturing Project, Best Wiki and Best Entrepreneurship as well as a Gold Medal. To top it all…

Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.

Leiden professor of molecular astrophysics and astrochemistry Ewine van Dishoeck was presented with the Niels Bohr International Gold Medal on Friday 7 October. The medal, instigated by the Danish Society of Engineers IDA, was awarded by Queen Margrethe of Denmark at a ceremony at the Carlsberg Academy…

The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…

Four green research institutes in Leiden are joining forces to integrate evolution and biodiversity research, at local and at the national level. Pivot in this collaboration is Frederic Lens.

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

If an echo (or ultrasound) shows that a foetus has a heart or other defect, parents face difficult decisions. Then an idea of their child’s shorter and longer-term future is literally a matter of life and death. Haak will argue in her inaugural lecture that the cohort studies of rare diseases that are…

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

Rapid developments in DNA techniques allow researchers to find out more and more about human genetics. An international group of scientists has drawn up five ethical guidelines to ensure that this DNA research is better regulated. Leiden archaeologist Marie Soressi – one of the signatories - explains…

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…

In a new study published in PLOS One, Leiden archaeologist Anastasia Nikulina, together with an international team from France, Denmark, the United Kingdom and the Netherlands, challenges the long-held belief that early humans had minimal impact on their environment before the rise of farming.

Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

Leiden biologists have found a mutation in flour beetles that allows them to speed up their development. The study has been published in Nature Ecology and Evolution.