The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

Can epigenetic changes explain associations between early life stress and health outcomes?

In September 2021, ACPA PhD Candidate Gabriel Paiuk will premiere a new work titled Sound Theory (The Clouds) as part of the 2021 Gaudeamus Muziekweek Festival. The performance will take place on September 10th, 20:30 at the De Helling (Utrecht, NL).

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Leiden Professor of Number Theory Manjul Bhargava has been awarded a Fields Medal, widely regarded as the Nobel Prize for Maths. Bhargava is a professor in Princeton, and since 2010 has also been the holder of the Stieltjes chair in Leiden.

Knowledge and culture subproject 3:

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

In this article, Jasmijn Boeken, explores in which ways the defining characteristics of the different zones can be found in the digital sphere.

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.

On Tuesday 15 September 2015, Bart de Smit has been appointed as professor of Algebra and Number Theory at the Mathematical Institute of Leiden University.

The goal of this book is to place architectural studies, in which people’s interactions with each other and material resources are key, at the crossing of both landscape studies and material culture studies, where it belongs.

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

What is the origin of educational ideas, e.g., the idea that intervention in infancy has long-lasting effects on development.

This dissertation provides a formal description of the relationship between diatopic/diachronic micro-variation and phonologization through analysis of the phonetic/phonological properties of unstressed vowel reduction and vowel insertion in two Northern Italian dialects.

Promotor: Prof.dr. P. Stevenhagen, Jan-Hendrik Evertse, Co-promotor: Pascal Autissier

Exploring the application of game-theoretic frameworks to quantum physics, this study creates novel AI training methods for the precise control of quantum systems.

Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.

This dissertation shows that dialogical logic constitutes a powerful and flexible general framework for the development and study of various logical formalisms and combinations thereof.

Pathogenic bacteria are increasingly resistant to today’s antibiotics. Professor Gilles van Wezel seeks new forms of antibiotics in good bacteria that live in the soil.

This dissertation provides crucial but as yet missing empirical data on the tone accent opposition in the so-called

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

LCD screens use liquid crystals which have a high degree of order, even though they form a fluid. A new theory maps out the interplay between order, temperature and symmetry. Publication in Physical Review X.

Catharanthus roseus (Madagascar periwinkle) produces valuable monoterpenoid indole alkaloids (MIAs) such as vincristine and vinblastine, crucial for cancer treatment.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Promotor: S.J. Edixhoven

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

Promotor: Prof.dr. A. Achucarro, Co-Promotor: J.W. van Holten

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…