In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

The project investigates the implementation of policies and practices related to reconciliation and the strengthening of government capacity in the Odesa and Kharkiv regions of Ukraine.

On the 2nd of September Jiyan Qiao successfully defended a doctoral thesis and graduated.

In Freedom on the Offensive, William Michael Schmidli illuminates how the Reagan administration's embrace of democracy promotion was a defining development in US foreign relations in the late twentieth century.

The eighth issue of the JLGC explores the diverse and interdisciplinary research on our multifaceted relationship with animals which is currently taking place, re-examining the relationship between humans and animals, and the definitions involved.

A new Special Issue with Transnational Legal Theory edited by Jelena Belic, Matthew Canfield, Henning Lahmann, Rachel Griffin, and Barrie Sander, brings together a collective of perspectives to unpack the promise and perils of human rights as a vocabulary for governing digital platforms.

On 21 Januari 2020, Patrick van Berlo defended his thesis 'Human Rights Elephants in an Era of Globalisation: Commodification, Crimmigration, and Human Rights in Confinement'. The doctoral research was supervised by Prof. J.P. van der Leun and Prof. M.A.H. van der Woude.

Amanda gave a talk in Vienna on the role of plant foods in human evolution, including a small teaser of the FoodWays project!

Identifying natural plant-associated bacteria that provide targeted inhibition of pathogens through the production of antimicrobial peptides.

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

When do fire making tools appear in prehistory, and how might the use of these tools manifest in the archaeological record?

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

This is a joint PhD of the Faculty of Social and Behavioral Sciences at Leiden University and the Evolutionary Ecology Group at Antwerp University.

On Monday 21 September Annemarie Meijer, Professor of Immunobiology, presented her inaugural lecture on immunobiology and infectious disease.

Have you ever stood in front of an abstract artwork and thought: “a monkey could have done that!”. As it turns out, you are wrong.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

Human-driven environmental damage is increasingly recognised as a global crisis. Should large-scale destruction of ecosystems be considered a crime? The concept of ecocide has gained renewed attention, particularly following a proposed definition for inclusion in international criminal law, raising…

Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.

How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?

Summer School

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

The individual in the EU: The application of insights from social psychology to improve the legitimacy and conflict-solving capability of the EU

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Get to know us through our online and in-person events for prospective students!

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.

Promotor: J.M. Memelink

When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

In Humanity’s End As A New Beginning, Emeritus Professor Mineke Schipper reflects on myths about ‘the end’.

Does foreign aid promote human rights?

When you think of humanities, you may not immediately think of a new super server. Yet one has just been commissioned. University lecturer Jelena Prokic from Leiden University Centre for Digital Humanities explains more about this development.

This summer school focuses on the emergence of sexual orientation, gender identity (SOGI) and intersex issues in different areas of international law, such as human rights law, refugee law, international economic law, and international criminal law. Details on the application for this edition are available…

Collecting as much information as possible about administering a new medicine to people can save a lot of money.

Analysis of drug adversity

NTER-SECTION is a peer-reviewed, open-access journal focusing on contributions from junior archaeological researchers at Leiden University. The journal offers an accessible platform for the publication of individual research by undergraduate and graduate students. The Editorial Board consists of PhD…

Imagining Urban Complexity introduces passionate and critical perspectives on the link between the humanities and urban studies.

The factors that dynamically sculpt the inter-regional correlation of brain patterns are poorly understood. Here, we test the hypothesis that they are shaped by the catecholaminergic neuromodulators norepinephrine and dopamine.

You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.

Vocal learning is a trait shared by songbirds and humans. It is also a trait that is restricted by the brain rather than by a species' vocal apparatus. In this dissertation, functional MRI is employed in both species in order to explore potential common neural mechanisms underlying the ability to develop…

This research explores how international organisations responded to the humanitarian and human rights challenges brought about by COVID-19.

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

How humans and rats cohabit the cityscape and what consequences this has for both sides of the conflict?

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

Research at the Macromolecular Biochemistry group is comprised of the following research themes:

If an algorithm has to learn to understand language, simply having a lot of data doesn’t help much. Like us, a computer has to learn the language in interaction with others. Tessa Verhoef is fascinated by how this interaction works.