With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Health Data Science Leiden University

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Why do many medical institutions struggle to use AI in their clinical practice? What are the essential steps for and before an effective implementation of AI in radiology workflow? How can AI implementation trigger enduring improvements in the clinical process? The book shows how change management is…

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

If you wish to know exactly what is going on in a healthy or sick human body, and at various levels such as molecule, cell, tissue, organ, larger systems and a person as a whole? Do you wish to learn how to do research which contributes to diagnoses, treatment and prevention of diseases? Then the bachelor…

Reactions and reaction times in cognitive tasks.

Mr. Jan van den Berg defended his thesis on 8 November 2018

Here you find the curriculum of the master's specialisations of Health, Medical and Neuropsychology.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

AI Labs are collaborations of Leiden University with external parties such as industry, governmental parties and other universities on the topic of Artificial Intelligence. The Science institutes of Leiden University are unique located in the largest Bioscience Park of the Netherlands, next door to…

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

Completing your Master’s in Biology gives you an internationally recognised degree which you can follow up with a PhD track. With your acquainted skills, you’re a much requested professional in and outside research.

Up to 45% of patients with Parkinson's disease experience impulse control disorders, characterised by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development…

A high-end label: Cyclophellitol aziridine-type activity-based probes allow for ultra-sensitive visualization of mammalian β-glucosidases (GBA1, GBA2, GBA3, and LPH) as well as several non-mammalian β-glucosidases (see picture). These probes offer new ways to study β-exoglucosidases, and configurational…

Inaugural lecture

Technology, medical knowledge, social measures and the design of the living environment: all these needed to achieve a healthier society. In a series of interviews, 14 researchers from Zuid-Holland, including from Leiden University, argue for an integrated care approach.

In welke mate hebben domaniale structuren de machtsvorming en nederzettingsontwikkeling in en van het gewest Holland bepaald?

On Friday the 6th of September 2024, members of the Leiden University Medical Anthropology Network convened in the African Studies Center to discuss Global Health Interventions.

As children learn, develop and acquire more skills, their legal position also changes. Professor of Children’s Rights Ton Liefaard works closely together with Leiden social sciences researchers to shed light on these growing capacities and their implications for our legal system. ‘Our ideas about children’s…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

This research line is part of the living lab of the University’s Population Health interdisciplinary program, located at the LUMC Campus The Hague, where the Leiden University Medical Center collaborates with the Faculty of Governance and Global Affairs and the Faculty of Social and Behavioral Sciences…

Mashaghi lab conducts research at the interface of physics, engineering and biomedicine. We develop and use theoretical and experimental approaches to address basic and applied research problems.

This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.

Psychologist Bernadet Klaassens initiated a large fMRI study on the effect of drugs on brain networks in aging and Alzheimer's disease. It generated a unique data set and insight into a new method to develop drugs for patients with Alzheimer's.

The Leiden University Center for Statistical Science unites the statisticians teaching and researching at Leiden University.

Discover the master program population Health Management at Leiden University and contribute to a more integrated health care system. Learn more!

Risk has become one of the defining features of modern society. This course examines various types of safety and security risks, and how these are perceived and dealt with in a wide array of professional and academic fields, ranging from criminology, counter-terrorism and cyber security, to philosophy,…

Voor deze use case zoeken wij een gebruiker die voor onderzoeksdoeleinden interesse heeft in de auteursrechtelijk beschermde collectie van de KB en ons kan helpen met het opstellen door wensen, noden en ervaringen te delen.

With the rise of information and communication technologies, large amounts of data are being generated and stored in databases. In order to get a better grip on these large amounts of data, serious efforts are being made to discover patterns and relations in the data with the help of new techniques.…

Repairing organs, tissues and cells to fight chronic diseases.

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

Our scientists working with laboratory animals undergo training on animal experiments. In this training, researchers learn how to handle laboratory animals responsibly. Read more about the requirements we set for researchers working with laboratory animals.

Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.

We aim to create an innovative e-learning and virtual reality training that helps healthcare providers to optimize placebo effects and minimizes nocebo effects via their communication.