703 search results for “smit barrier re-pair” in the Public website
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“The Binnenhof” a contested court. History, housing and politics in The Hague, 1813-2013
This project examines the meaning of this historical place, and the way it has been used by the political institutions that have had their seat there.
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Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…
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Interventions
Our mission is to bring together research and practice focused on the improvement of mental health and the enhancement of treatment / psychotherapy success. To reach this goal we focus on the following paths:
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Cleveringa Dallaire Critical Conversation Series
In the fall of 2021, Cleveringa professor Roméo Dallaire and world experts shared their thoughts about PTSD, children’s rights, war crimes, humanitarian law, and peacekeeping in a series of conversations about leadership and moral dilemma during times of conflict and crisis.
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Stress and trauma-related disorders
Our mission is to advance the understanding of mental health of individuals with a history of stress and/or trauma through rigorous interdisciplinary research, integrating insights from clinical psychology, neurobiology, and social sciences. We are committed to translating our findings into innovative…
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Host-Microbe Interactions in Plant Sciences
Plant Sciences' contribution to the Host-Microbe Interactions research theme is to dissect how microorganisms and microbiomes interact with the plant host and the insects on those plants, and how these insights may be harnessed to improve plant growth and health, by steering microbiome composition and…
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Douwe AtsmaFaculty of Medicine
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Dissociative chemisorption on transition metal surfaces
The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…
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Anna van BuerenpleinAnna van Buerenplein 301, The Hague
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Computational approaches to dissociative chemisorption on metals: towards chemical accuracy
We review the state-of-the-art in the theory of dissociative chemisorption (DC) of small gas phase molecules on metal surfaces, which is important to modeling heterogeneous catalysis for practical reasons, and for achieving an understanding of the wealth of experimental information that exists for this…
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Sex, Care & Robots
Sexuality is a fundamental part of being human. Yet, for many people with disabilities, it remains overlooked, unsupported, and surrounded by stigma. NWO-VIDI Sex, Care & Robots confronts that long-standing neglect with a project that envisions an urgent yet straightforward future: one in which sexual…
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UBC Europe – University-Business Cooperation in Europe
To goal of this project is to get a deeper, more comprehensive and up to date understanding of the state of University-Business Cooperations (UBC) in Europe, from the perspective of both the Higher Education Institutions and the business sector.
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Glucocerebrosidase and glycolipids: In and beyond the lysosome
The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.
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Resumptive Prolepsis. A Study in Indirect A'-Dependencies
This dissertation investigates A'-dependencies in Standard German, Zurich German and Dutch where the dislocated constituent is indirectly, i.e. not transformationally, related to the position where it is interpreted. The analysis is carried out within the Principles & Parameters framework.
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Towards Open and Reproducible Terrorism Studies: Current Trends and Next Steps
In recent years, the use of primary data in terrorism research has increased. In order to maximise the benefits of this trend, we want to encourage terrorism scholars to implement open science practices more systematically. This article therefore presents different avenues towards open and reproducible…
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Lipid mediated colloidal interactions
The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.
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Phase behavior of skin lipid mixtures: the effect of cholesterol on lipid organization
The lipid matrix in the stratum corneum (SC), the upper layer of the skin, plays a critical role in the skin barrier. The matrix consists of ceramides (CERs), cholesterol (CHOL) and free fatty acids (FFAs).
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The Borders of Race in Colonial South Africa. The Kat River Settlement, 1829–1856
This monograph by Robert Ross provides a detailed narrative of the Kat River Settlement in the Eastern Cape of South Africa during the nineteenth century.
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Key publications
Key publications of the Analytical BioSciences and Metabolomics group
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Gorlaeus BuildingEinsteinweg 55, Leiden
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Optimisation of first clinical studies in special populations: towards semi-physiological pharmacokinetic models
Promotor: M. Danhof, Co-promotores: J. Freijer, A. Yassen
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Advances in 2D Material Synthesis, Transfer, and Device Integration
This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.
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Advancing Explanatory and Tonal Dialectometry
On the 13th of February, Matthew Sung successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Matthew on this achievement!
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Open Science Monitoring and Evaluation
Over the next two years, CWTS and Dialogic will develop a robust and context-specific monitoring and evaluation framework for Open Science in the Netherlands. This will be accompanied by the development of a prototype dashboard to showcase how such an Open Science monitor could be made visible.
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African languages archives
This collaborative research group (CRG) facilitates the synergies of researchers engaged with African languages and documentation of texts conducted in East Africa, paying particular attention to ‘endangered archives’ and ‘endangered languages’.
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Class invariants for tame Galois algebras
Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit
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Catherine MergenFaculty of Science
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Koen van der MaadenFaculty of Science
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Mikolaj SzachniewiczFaculty of Science
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Making and creating with ages-old knowledge
The ability to create objects and structures with our hands has been essential to human development. This ability is something modern society is at risk of losing. Leiden archaeologists gather knowledge about ancient processes of ‘making and creating’ over the centuries, knowledge that helps our current…
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Personal ornaments: changing identities in the Dutch Neolithic and Bronze Age
Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.
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Nostalgia for the Present
Ethnography and Photography in a Moroccan Berber Village
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Contemporary International Criminal Law After Critique
In this article, the authors explore how international criminal law is moving into a ‘post-critical’ phase and examine its potential for emancipatory reform.
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…
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Mobility
An estimated 17% of our university's total carbon footprint comes from the thousands of travel movements by our staff, students, visitors, and suppliers. Our aim is to reduce these emissions by a quarter in the coming years.
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Illuminating Host Defence against Mycobacterial Infection: Interactions with Autophagy and LC3-Associated Phagocytosis
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.
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Drug Delivery to the Brain
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB
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Current Approaches to Roman Frontiers (LIMES XXV volume 1)
Proceedings of the 25th International Congress of Roman Frontier Studies 1
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Student projects
Are you looking for a research project? We have projects available for motivated 6–9-month internship students with particular interest in organic/polymer synthesis, formulation development, gene delivery, protein delivery, and the preliminairy in vitro screening of drug delivery platforms. Students…
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Witnesses and Victims Protection in Indonesia's Criminal Justice System: Perspectives, Legal Realities, and Social Justice Initiatives [WVP &
How does the criminal justice system in Indonesia safeguard the rights of and access to justice for witnesses and victims?
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Introduction: WPS 20 Years On: Where Are the Women Now?
This special issue focuses on emerging trends in the implementation of the WPS agenda. In reviewing the resolution 20 years since the passing of Resolution 1325, Newby and O'Malley have highlighted the gaps in implementation.
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Towards chemically accurate simulation of molecule-surface reactions
This perspective addresses four challenges facing theorists whose aim is to make quantitatively accurate predictions for reactions of molecules on metal surfaces, and suggests ways of meeting these challenges, focusing on dissociative chemisorption reactions of H2, N2, and CH4.
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Public Purpose
Implementing all kinds of change and introducing new structures, far-reaching rules and administrative systems may sometimes seem to distract an organisation from its purpose. Furthermore, there is growing recognition of the need of staff of public organisations to find more meaning in their work: the…
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Strategy and Structures along the Roman Frontier (LIMES XXV volume 2)
Proceedings of the 25th International Congress of Roman Frontier Studies 2
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igraph - To modernize the igraph interfaces to make network analysis easier
igraph development focused on improving the most-used interfaces, which are Python, R, and Mathematica. Additionally, the developers aim to make the library and the interfaces easier to maintain, focusing on long-term sustainability. This ensures that igraph continues to be a useful tool for network…
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Supplying the Roman Empire (LIMES XXV volume 4)
Proceedings of the 25th International Congress of Roman Frontier Studies 4