With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

This interdisciplinary research project explores several adaptive machine learning methods which can give insight into the interaction between human and machine. The ultimate goal is open and natural communication between humans and AI that should result in mutual trust, cooperation and coordination…

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

The two-year Data Science: Computer Science programme consists of 120 European Credit Transfer System (EC) points and includes courses and electives as well as a Master's Thesis Research Project.

Promotor: Prof.dr. T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

To what extent can digital technologies be considered as authorities?

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

The quantum nature of matter and light has grown into a broad and fruitful research field for theorists and experimentalists alike. It combines foundational research with toward applications, the most well known of which is the quantum computer.

Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.

The specialisation combines one year of Computer Science research (60 – 80 EC) with one year of science communication courses, internships and research (40-60 EC).

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

The two-year Artificial Intelligence programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project.

The research of the Algebra, Geometry and Number Theory cluster tries to bridge the gap between abstract theory and the world of algorithms and applications.

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

This article explores how the meaning of the rule of law has evolved over the past century in UK and US parliamentary speeches, focusing on procedural (thin) and substantive (thick) conceptualisations.

Are you eager to bring your own questions and curiosity into scientific research? Do you question intelligence and technology in a fundamental, creative, and playful way? Could you be a researcher who challenges scientific practice and pushes its boundaries?

The two-year Bioinformatics programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project. PLEASE NOTE: The specialisation Bioinformatics will no longer accept new students after February 2026. If you're starting date is September 2026 or later, we…

Lecture

The biweekly Lunch Time Seminar is an online only event, but it is not publicly accessible in real-time. If you would like to attend one of the upcoming sessions, please send an email to sails@liacs.leidenuniv.nl.

Lecture

LCN2 hosts seminars on the last Friday of each month.

On 29 January 2019, Robbert van Eijk defended his thesis 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. The doctoral research was supervised by Prof. dr. H.J. van den Herik.

Creation of a framework for environmental parameter estimation that benefits from the consistency of physics-based theory-driven models and the accuracy of the machine-learning-based data-driven models

The Ada Lovelace Distinguished Lecture Series brings outstanding computer scientists from around the world to Leiden University. The lecturers will share exciting ideas and results from the forefront of computer science.

This project develops methods for ensuring the anonymity of individuals in social network data.

Promotor: Prof.dr. E.F.A. Deprettere, Co-promoter: Todor P. Stefanov

To what extent is creative ownership in contemporary (graphic) design practices changing now that we are co-creating with machines? And can machines have copyrights, too?

The rise of the digital age affects public governance in many ways. Digitalisation and data impact every aspect of public governance and policy. Within Leiden University’s Public Administration institute, based in The Hague -the administrative capital of the Netherlands- our centre seeks to understand…

Embedding ethical legal and societal aspects for responsible military AI.

The Leiden Institute of Advanced Computer Science (LIACS) is a centre of excellence for multidisciplinary research and education in computer science and artificial intelligence (AI).

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Several times per year, the Europa Institute organises a ‘Meet the Author’ event. In the context of this event series external academics come to Leiden to discuss one of their recent publications. The event starts with a conversation between a member of the Europa Institute and the author, after which…

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich

Machine Learning is becoming a more and more substantial technology for industry.

Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…

On 12 November 2019, Larissa Koupriuchina defended her thesis 'Judgmental Adjustments in Revenue Management'. The doctoral research was supervised by Prof. J.I. Van der Rest.

Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…

The data-driven economy allows for the collection and processing of large amounts of data. Such data can be used to optimize profits by (dynamically) differentiating prices for different consumers.

This GUTS Special Issue focuses on the dynamic relationship between neurobiological development and social experiences in shaping young people's engagement and contributions to society. It explores how young individuals grow up in an increasingly complex world and how various factors – such as family…

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Responsible AI for science and a strong and resilient society.

The Europa Institute of Leiden University is one of the oldest academic institutes specialised in the law of the European Union and the European Convention on Human Rights; it was established in 1957, the same year as the European Economic Community itself.

Healthcare Information Systems (HIS) are essential for modern healthcare delivery, yet their development faces significant challenges including heterogeneous data formats, regulatory compliance, and the growing demand for AI-driven decision support.

The master's specialisation Bioinformatics at Leiden University focuses on research, development and application of computational tools and approaches for expanding the use of biological, medical, behavioral and health data.

The master's specialisation Data Science: Computer Science at Leiden University provides students thorough knowledge and understanding of statistical and computational aspects of data analysis, including their application in databases, advances in data mining, networks, pattern recognition, and deep…

Friday afternoon, 1 October. Location: one of the most vibration-free places in the world. In this setting, Leiden top scientists launched Quantum Leiden. For decades, researchers at the Faculty of Science have been investigating quantum technology at the highest level and also have been brainstorming…