Understanding the water use of power production is an important step to both a sustainable energy transition and an improved understanding of water conservation measures. However, there are large differences across the literature that currently present barriers to decision making.

To overcome the limitations of slow and error-prone quality control, this research develops an advanced 3D imaging method for the rapid and reliable detection of internal defects in critical sectors.

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Promotor: Prof.dr. J. Kuiper

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.

An international team from the Netherlands, France, Norway and Austria demonstrate how new sequencing technologies can be used to efficiently generate the genome, DNA, sequence of an endangered animal, the European Eel.

Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar

On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…

The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…

Publication by: Amanda Foks, Gijs van Puijvelde, Jolien Wolbert, Mara Kröner, Vanessa Frodermann, Thomas van der Heijden, Peter van Santbrink, Louis Boon, Ilze Bot and Johan Kuiper. Cardiovascular Research. 2016;111(3):252-261.

Leiden University Medical Center (LUMC), as a partner in the reNEW consortium, is once again receiving tens of millions of euros for research into new treatments based on stem cells. The collaboration will receive a total of €150 million to develop new therapies in regenerative medicine.

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

Leiden and Austrian researchers have succeeded in further uncovering how a plant cell passes on the growth hormone auxin in a directional manner to the next cell. Three proteins that cling together in a bunch appear to be essential for this important transport process. ‘This discovery solves a crucial…

Researchers from the Leiden Institute of Chemistry show proof of principle that live-cell structural changes and metabolic processes can be followed in real time with NMR spectroscopy. They performed their study on photosynthetic green algae that are metabolically flexible and can sustain energy generation…

How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.

Toxys, Leiden University and Leiden University Medical Center have agreed immediately to commercialise and also develop further the ToxProfiler technology invented at the two institutions. ToxProfiler allows for rapid toxicity hazard identification of novel and existing drugs, chemicals, and other substances.…

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Jingxian Wang, PhD at ICLON, examined technology integration in primary and secondary education. Defence on 6 July.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

Reducing greenhouse gas emissions is one of the most pressing challenges that humanity faces in the coming decades.

This page contains all relevant information for lecturers teaching in the Astronomy bachelor's and/or master's curriculum at Leiden University.

On April 26, three separate projects from LIACS Media Technology group members were awarded a

Our annual "Science to Experience" exhibition of student works is hosted by the V2_ Lab for the Unstable Media. This year's theme is "TIME".

On February 24 2022, the Technology group organized a GTGC Tech Talk. During this meeting Anna-Lena presented her first PhD paper "Bringing the Social Back in: Big Science Collaborations as Social Spaces of Strategic Action".

On Wednesday the 1st of December, the thematic area on technology of GTGC organized its first research seminar, by Anna-Lena Rüland and Babak Rezaeedaryakenari. James Shires, together with his colleague Max Smeets at ETH Zurich, presented on their project "Cyberspace and (In)stability: The Structural…

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.