The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

In the Brill series Intersections a new volume has been published, entitled Ronsard and Du Bartas in Early Modern Europe.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

How did a circle of Soviet artists and writers virtually unknown until perestroika turn into Russia’s most influential contemporary art movement? This book reconstructs the cultural history and canonization of a group of painters and poets known as the Moscow conceptualists, who paradoxically did not…

This study by artist Jonas Staal explores the development of propaganda art from the 20th to the 21st century.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

What does the interspecies interpretation of the equality principle mean for the liberal democracy, and is it possible to provide for an appropriate legal and political position for animals without defying the classic-liberal principles of the liberal democratic state?

Kartika Setyawati defended her thesis on 12 November 2015

This new handbook by Frits Naerebout and Henk Singor places the history of the Greeks and Romans within the larger context of the contemporary Eurasian world.

English The purpose of this research is to identify and examine the challenges faced by African States in the field of foreign investment with a view to contribute not only to the academic debate, but also to foster awareness and develop the capacities of these States with regard to the drafting, negotiation…

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Yoshiyasu Yonezawa defended his thesis on 24 October 2019

This study presents a full descriptive account of the grammar of Mualang, covering the major features of phonology and morphosyntax as well as issues related to pragmatics.

Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.

he Central Innovation District (CID) forms the economic heart of the city of The Hague.

Both the Dutch government and the European Commission dedicate an increasing share of public funding for research and innovation to mission-oriented programs, aiming to facilitate sustainability transitions. These programs typically involve support fora range of different research activities, from the…

Leiden Law School is currently housed in two beautifully restored historic buildings located in the old centre of Leiden. We also have facilities for teaching and research at Campus Den Haag.

We recognize the importance of communicating about our scientic work to the general public and we enjoy doing so. Recently, we received funding from the Pilot fund Science communication by scientists: Appreciated! (with members of Change Leiden) to engage children and adolescents in science communication…

Kim de Jong, Jaime Delgadillo, and Michael Barkham offer valuable insights in their book 'Routine Outcome Monitoring and Feedback in Psychological Therapies' on how therapists and trainees can use feedback to inform treatment decisions and, ultimately, enhance patient outcomes.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

The present monograph, spanning a wide range of world and local literatures represents a high academic standard of both literary criticism and philological analysis. By demonstrating her expertise as an Africanist conversant with the Arabic canon, Raia reveals how the narrative of Joseph has been re-narrated…

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We are moreover strongly involved in the Master specialisation of Pharmacy at Leiden University. We work on clinical problems that require further mechanistic understanding and…

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

The Center for Legal Entrepreneurship and Innovation believes it is important that lecturers, students and researchers are informed about the impact of technological developments in the legal industry in terms of the relevance of education, for academic research and the labor market perspective of students.…

This is the first full-scale reference grammar of Classical Greek in English in a century.

Today, 189 out of 193 officially recognised nation-states have a written constitution, and 75% of these have been ratified since 1975. How did this worldwide diffusion of constitutions come about?

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Nirajan Kafle defended his thesis on 15 October 2015

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

This dissertation contains a detailed description of the Carib language, including the most extensive dictionary of the language to date. This knowledge is based on work from earlier sources and field work which was carried out by the author over a ten-year period, particularly in Galibi, a Carib village…

How do mycobacteria subvert the defenses of host immune cells?

Newly published: ‘Background to Beakers’; inquiries into regional cultural backgrounds of the Bell Beaker Complex. Harry Fokkens / Franco Nicolis (eds.).

The Discovery of El Greco: The Nationalization of Culture Versus the Rise of Modern Art (1860-1915)

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

This article tries to examine if one can take the 'One Net' for granted, since the world becomes increasingly fragmented with social and geopolitical tensions. Furthermore, the author seeks to discover what is at stake if the global interoperable network is under a threat of fragmentation.

A new publication that brings together perspectives on language contact phenomena across temporal and spatial dimensions.

Promotor: S.M. Verduyn Lunel, Co-promotores: M.F.E. de Jeu, B. de Pagter

This programme aims to make the digitized archival sources of the Kerala and Tamil Nadu Archives more accessible to Indian and international scholars and to the widest possible audience, in particular to the people of Kerala.

From basic science to real-world interventions

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

This research cluster explores processes of cultural creation, reception and transformation within a wide range of societal contexts from the early Middle Ages until c. 1800.

Our Talents and Discoveries was a yearly publication by the Faculty of Science of Leiden University, published since 2003. You can read all the editions online. Note that the original publication was in Dutch; the original title translates as 'What we are proud of'. The last booklet came out in 2022,…

Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn, Co-promotor: Dr. M.J.M. Schaaf

In this article, Thijs van Dooremalen and Philip Smith investigate how public discourse of heatwaves have shifted in British newspaper discourse, drawing on Raymond Williams’s theory of dominant, emergent, and residual cultural patterns to analyse changes in language and interpretation over recent d…

This book presents a comprehensive description of the grammar of Logba, one of the fourteen Ghana-Togo Mountain (GTM) languages spoken by approximately 7,500 speakers on the South-Eastern frontier of the Ghana-Togo border. It is the outcome of fifteen months research in Logba speaking communities.