This is an Erasmus+ International Credit Mobility project of Leiden University's Faculty of Science with University of Pretoria in South Africa.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Humanities with two different partner institutes in Uzbekistan: Tashkent State Institute of Oriental Studies and The Abu Raihan al-Biruni Centre for Oriental Manuscripts.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with the Anton de Kom University in Suriname.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with National University of Singapore in Singapore.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with Ilia State University in Georgia.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Law with two different partner universities in Uganda: The International University of East Africa and Makarere University.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Medicine with University of Indonesia, Faculty of Medicine, and Universitas Katolik Indonesia Atma Jaya in Indonesia.

These are two separate Erasmus+ International Credit Mobility projects with Monash University in Australia, one of Leiden University’s Faculty of Law, the other of the Leiden Academic Centre for Drug Research (LACDR).

This is an Erasmus+ International Credit Mobility project of Leiden University's Faculty of Law with Universidad de Diego Portales in Chile.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Law with the University of Rwanda in Rwanda.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with the University of Alberta in Canada.

This is an Erasmus+ International Credit Mobility project of Leiden University's Faculty of Science with Universidad de la Habana in Cuba.

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…

Image-Pro Plus, ImageJ, Cell Profiler, R, Knime and NIS-elements

Discovery of metastasis promoting candidate drug targets

Projects within the theme ‘Computational Biology’ aim to employ mathematical or computational dynamical modelling approaches to discover novel concepts that are important for drug development.

Promotores: A.H. Meijer, H.P. Spaink

Promotor: B. van de Water

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

Our Division has created and maintains the Visualisation Core Facilities of the LACDR. This is a multi-user facility offering basic and advanced microscopic techniques to scientists of the LACDR.

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Law with Holy Spirit University of Kaslik.

Explore the MSc in Nationalism, Ethnic Conflict and Development at Leiden University: study governance and diversity, choose elective seminars, complete a thesis and optionally an internship.

What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

This is an Erasmus+ International Credit Mobility project of Leiden University's Faculty of Law with Holy Spirit University of Kaslik in Lebanon.

This is an Erasmus+ International Credit Mobility project of Leiden University's Faculty of Social and Behavioural Sciences with University of Botswana in Botswana.

In 2020, Leiden University launched its stimulated interdisciplinary programs, including one focused on regenerative medicine.

Getting personal

Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

We have developed a microfluidic platform for complex 3D organotypic cell cultures (so-called organ-on-a-chip systems) which are suited for integration in 96 or higher well plate format.

This is a facility where research groups or small companies can apply for space if they need to culture human or animal cells.

This is an Erasmus+ International Credit Mobility project of the Faculty of Science with three universities in Colombia.

Physics and Engineering Approaches to Biomedicine and Pharmacology

The European Union has awarded a COFUND grant to a consortium of researchers from the universities of Groningen and Leiden for a collective PhD programme called ‘Evolve’. The 7.1 M€ programme, which is co-financed by the participating universities, is recruiting and training 17 PhD students to conduct…

Intrigued by the way cells autonomously regulate their fate, we strive to understand and visualize cellular processes as the basis of Cell Signaling.

Promotor: B. van de Water

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.