703 search results for “multi-objective optimization” in the Public website
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Education
Education & outreach
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Imaging & Intervention (MSc)
This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.
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Bio-Pharmaceutical Sciences and Education (MSc)
The master’s specialisation Bio-Pharmaceutical Sciences and Education at Leiden University combines fundamental chemistry research with an excellent education in becoming a Chemistry teacher.
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Key publications
Key publications of the Medical Systems Biophysics and Bioengineeringgroup (Mashaghi Lab)
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Astronomy and Education (MSc)
The master’s specialisation Astronomy and Education at Leiden University prepares you to teach the subject of biology to secondary school students. The programme comprises a one-year Astronomy component, followed by an education component in the second year.
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Biology and Education (MSc)
The master’s specialisation Biology and Education at Leiden University prepares students to teach the subject of biology to secondary school students. The programme comprises a one-year Biology component, followed by an education component in the second year.
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The versatility of asymmetric aminoethyl-tetrazines in bioorthogonal chemistry
This thesis describes the synthesis, analysis of various tetrazine bearing compounds and use in bioorthogonal chemistry.
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Bio-Pharmaceutical Sciences (MSc)
The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.
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Images of Galois representations
Promotores: S.J. Edixhoven, P.Parent
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Computer Science and Education (MSc)
The master’s specialisation Computer Science and Education at Leiden University prepares students to teach the subject of biology to secondary school students. The programme comprises a one-year Computer Science component, followed by an education component in the second year.
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C-SCAPE - Sandy strategies for sustainable coastal climate change adaptation
What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?
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Bright Horizons: Adjunctive Light Therapy for PTSD
Exploring the synergy of light therapy and exposure psychotherapy to enhance PTSD treatment outcomes.
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Krijn Rietveld Memorial Awards
Turning scientific insight into real-world impact. With The Krijn Rietveld Memorial Awards, dsm-firmenich honours outstanding researchers - from master's to postdoctoral researchers and start-ups - across life sciences, (environmental) health sciences and biotechnology, with data science at the core…
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Tropical Tensor Networks and Bell Inequalities: From Multipartite Nonlocality to Quantum Device Certification
PhD defence
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Science Communication and Society
The research group Science Communication and Society has been physically within the Institute of Biology (IBL) since 2012 and has become a formal part of the institute in 2018. The mission of this group is understanding how science communication works to improve the interaction between science and s…
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United States
This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.
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Cooperation partnerships
Erasmus+ Cooperation partnerships are transnational projects designed to develop and share innovative practices and promote cooperation, peer learning, and the exchange of experiences in education. There are two kinds of Cooperation partnerships: those supporting innovation and those supporting the…
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Hao Wang -
Marian HickendorffFaculty of Social and Behavioural Sciences
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Podcast series Computers don't byte
Leading computer scientists from a variety of fields share their expertise and insights. Dive into the minds of these researchers and learn about real-world applications, the future of AI and related technologies and cutting-edge research. From chatbots to cybersecurity, from quantum to children's stories,…
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Todor Stefanov -
Iryna Kovalchyk -
Xi’an Jiaotong University Day at Leiden University
16 April was a special day at the Faculty of Science. In honour of the collaborations with the Chinese partner university, it was declared Xi’an Jiaotong University Day.
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PET/CT to Optimize Treatment Management of High-Risk Stage III and IV Melanoma
PhD defence
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Optimizing MRI-guided radiotherapy for dose escalation in rectal cancer
PhD defence
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Research
Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…
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Biodiversity
Biodiversity is under pressure worldwide, but is essential for our health, food security and well-being. What is the influence of human actions on ecosystems? Can we provide biodiversity-inclusive solutions for our key societal challenges? These questions are central to the Biodiversity research the…
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Research
The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.
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Education
CML’s education programme aims at training (under)graduate and graduate students for integrated and multidisciplinary sustainability research and for better decision making in managing the world’s natural resources, environmental quality and biodiversity.
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Archaeological Heritage and Society
The researchers and students at the Department of Archaeological Heritage and Society at the Faculty of Archaeology study the role of the past in modern societies. They want to find out more about the relationships between the past and the present, and the role that heritage plays.
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Organisation
The Institute of Education and Child Studies is part of the Faculty of Social and Behavioural Sciences at Leiden University. The institute is governed by an Institute Board under the direction of a rotating chairman, i.e. the Scientific Director and an Director of Studies. The Institute Board is…
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Farmers, fishers, fowlers, hunters
Knowledge generated by development-led archaeology about the Late Neolithic, the Early Bronze Age and the start of the Middle Bronze Age (2850 - 1500 cal BC) in the Netherlands
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Material support
PhD candidates have access to various forms of material support.
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Personalized Medicine
Getting personal
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Research
An overview of the research at the Biologics Formulation group
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More effective blocking of CCR2 receptor
The discovery of new medicines is a tedious and lengthy process. On average, over 10,000 molecules need to be studied for one to become a drug and reach the patient. Part of that process are the very costly clinical trials in humans, and candidate drugs often fail due to side effects or lack of efficacy.…
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Selectivity
Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.
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Research
Research lines within the Pharmacy group:
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Key publications
Key publications of the Quantitative Pharmacology group
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Biomedical Microscale Analytics
The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Plant Macro-Fossils and Climate Change
This part of the research programme is carried out by Prof. Dr. René Cappers. It focusses on the continuities and changes in the use of plants at Late Neolithic Tell Sabi Abyad, as well as on their implications as proxy evidence for the climate change c. 6200 BC. Parallel to the design of the other…
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Key publications
Key publications of the Quantitative Clinical Pharmacology group
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Algorithms for quantum software
Top scientists of three Dutch universities are working on software and systems for quantum computers. Researchers of the Leiden Institute of Advanced Computer Science (LIACS) and the Leiden Institute of Physics (LION) are developing new algorithms to make those super computers work. The coming years,…
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Determinants of and Interventions in Chronic Fatigue.
What are the most important perpetuating factors of chronic fatigue and chronic fatigue syndrome, and which interventions are effective in influencing these factors?
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TAFL Teaching Arabic as a Foreign Language
From Tuesday 6 January till Tuesday 15 January 2026, NVIC organizes a new edition of the TAFL course. This intensive, interactive course is developed for (future) teachers of Arabic. It addresses both the practical aspects of teaching Arabic as a foreign language as well as the underlying linguistic…
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Host-Microbe Interactions
Microbes influence and respond to other organisms. This theme explores the dynamic relationships within plant and animal microbiomes, and the immune responses that govern host defense. Using model systems such as zebrafish, insects, and plants, we investigate fundamental processes and engineer microbes…
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Organisation
Organisation Institute of Biology Leiden
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Efficient Chemistry for new antibiotics against C. difficile
How can efficient chemical synthesis and clinical microbiology be combined to identify new antibiotics against Clostridioides difficile infections?