When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

Resistance to antibiotics is a major problem in health care. Thanks to a grant from the Elise Mathilde Fund and the LUF, pharmacologist dr. Coen van Hasselt can look for new dosing schedules to reduce the development of antibiotic resistance.

When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.

How can we diagnose the life-threatening condition sepsis in premature babies as quickly and accurately as possible? That is what PhD student Manchu Thangavelu from the Leiden Academic Centre for Drug Research (LACDR) wants to figure out.

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Lecture, NGL-lezing

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.

Does a snake die when it bites its lip? Why will a mongoose survive a scorpion’s sting, but we humans perish? These questions occupied the minds of toxin-enthusiasts and Master’s students Biology Jory van Thiel and Roel Wouters. They collected information from many sources and published their findings…

Workshop

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

Biopharmaceutical sciences master's student Nicole ter Laak has won the KNMP Studentenprijs 2023. She wins the prize for her research project on dosing guidelines of antibiotics in newborn babies with a very low birth weight for gestational age.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.

On 26 November 1940 Professor Cleveringa held his courageous speech protesting against the dismissal of his Jewish colleague, Professor Meijers. Cleveringa was arrested and the university was closed. Every year the university honours Cleveringa with a chair and meetings throughout the world.

Students for Palestine – a group of students from Leiden and The Hague – are holding a panel discussion in the Leiden University in The Hague Wijnhaven building on Tuesday 24 May entitled ‘Silencing Palestine’.

Soil that is too wet, or too dry. Or with a lot or few nutrients. Due to climate change, the differences are becoming bigger, and plants must increasingly be able to adapt to survive. How do you make plants more stress-resistant? For this purpose, researchers from Leiden, along with other universities,…

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

From scanners in lecture halls to systems for working from home: the discussion about new technology is being held on various fronts. That is why the University wants to make more use of its in-house experts. At the Technology and Trust symposium at Leiden University on 2 February, researchers from…

From memorials to the armed forces to memory stones for individual victims. It was only later that the Holocaust took a central role in Western remembrance culture, Cleveringa Professor Frank van Vree notes. ‘Nationalists and human rights activists both invoke the experience of the Holocaust.’

The Indonesian Student Association in the Netherlands, ‘Perhimpunan Pelajar Indonesia Belanda’, has teamed up with the Indonesian embassy in The Hague and Historia.ID magazine to create an exhibition to mark the association’s 100th anniversary. The student association, which was founded in Leiden, played…

As University historian, Pieter Slaman researches the University’s past, but he’s equally interested in its present. ‘It’s useful to be familiar with issues from the past. Not to be rooted in the past because some developments from history are things you definitely don’t want to repeat.’

Physicist Milan Allan will build an instrument that will bring superconductivity research further. He has been awarded an ERC Consolidator Grant of 2 million euros over the next five years. With his PairNoise programme he aims to detect paired electrons as they occur just above the temperature at which…

Every year on or around International Women’s Day on 8 March, Leiden University holds its Annie Romein-Verschoor Lecture. This year’s lecture will be given by Sylvana Simons, MP and leader and parliamentary chair of the BIJ1 party. What does International Women’s Day mean to her and which challenges…

Education

Amidst the lathes and welding machines of the Fine Mechanics Department, Emiel Wiegers is working concentratedly on a metal cylinder. He and his colleagues design and construct components for researchers' set-ups. ‘We are a bunch of inventors who enjoy helping the researchers in our Faculty.’

It was not until 1878 that the first female students enrolled at Leiden University, but the discussion on whether women were suited to study was by no means over. 8 March is International Women's Day. BBC correspondente Kim Ghattas will deliver a lecture on 6 March on the struggle by Arabic women for…

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…

Getting motivation, courage and tools to find a job that will help you tackle the climate crisis: it is at the heart of the course ‘Designing Your Career as a Climate Changemaker’. With their final presentations, the students conclude this climate-specific skills module within the Designing Your Life…

Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.

Young researchers met this month for the fifth Science Communication Summer School. ‘This is the first time some participants get to meet other researchers who also enjoy science communication. It’s great to see’, says Julia Cramer, one of the coordinators.