426 zoekresultaten voor “anti-cancer date some” in de Publieke website
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Pulling the strings on anti-cancer immunity
Promotores: J. Jonkers, K.E. de Visser
- Save the date: 450-talk
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Functional analysis of Dof transcription factors controlling heading date and PPDK gene expression in rice
Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang
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Anthracycline biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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On some classes of modules and their endomorphism rings
Promotores: Prof.dr. H Lenstra, Prof.dr. A Facchini (Padova University)
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi
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Dates 'Foundations 1' available
'Foundations 1' takes place on 1-3 March. Do you want to learn more about different types of sources and methods for source analysis in the Dominican convent in Huissen? Register now by sending an email to ozsmed@hum.leidenuniv.nl!
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Duality, bosonic particle systems and some exactly solvable models of non-equilibrium
Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander
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Some Assembly Required: The Structural Evolution and Mass Assembly of Galaxies at z
This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.
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Save the date: Mmmonk School 2024
Mmmonk en het Henri Pirenne Instituut voor Middeleeuwse Studies (UGent) organiseren eind 2024 de tweede editie van Mmmonk School: Lessen voor gevorderde beginners rond het middeleeuwse boek. Mmmonk School biedt een interdisciplinair praktijkgericht programma over middeleeuwse Vlaamse manuscripten. Experts…
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Twee psychologen op date met de rector
Rector magnificus Carel Stolker neemt op 8 februari afscheid. Als er één thema als een rode draad door zijn carrière loopt, dan is het de verbinding tussen universiteit en maatschappij. In deze serie afscheidsgesprekken gaat Stolker nog eenmaal in gesprek met mensen van binnen en buiten de universiteit.…
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This is life: some thoughts on self-organized structure formation in active liquids and biological systems
It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.
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Save the date: Symposium 'De Middeleeuwen als inspiratiebron'
Op donderdagmiddag 15 mei 2025 organiseert Universitaire Bibliotheken Leiden het symposium ‘De Middeleeuwen als inspiratiebron’. Aanleiding voor dit symposium is de publicatie van het rijk geïllustreerde publieksboek 'Schatten op schrift, 50 manuscripten uit middeleeuws Europa'.
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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In deze honoursclass ga je met je probleem op date
Theoretisch onderzoek geeft ons niet altijd de beste oplossing voor een probleem in de maatschappij. Dit is de boodschap die wordt verkondigd tijdens de eindpresentaties van de Master Honours Class 'Social Innovation in Action'.
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Small scale kinematics of massive star-forming cores
Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde
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Radio galaxies near the epoch of reionisation
This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.
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Save the date: 9-11 November 2016 ISGA Conference
Het Institute of Security and Global Affairs (ISGA) nodigt u van harte uit voor haar openingsconferentie ‘Towards new strategies for contemporary security challenges’ van woensdag 9 tot vrijdag 11 november 2016 in Den Haag.
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Save the date - Studiedag gesloten jeugdhulp op 27 mei 2019
Tijdens deze studiedag zullen – onder voorzitterschap van prof. mr. drs. Mariëlle Bruning – de bevindingen uit de beide dissertaties over gesloten jeugdhulp worden gepresenteerd en zal er vanuit verschillende perspectieven worden gereflecteerd op deze bevindingen en aanbevelingen.
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Masterstudent Maddalena Centanni wint Arenberg-Coimbragroep-prijs
Voormalig masterstudent Bio-Farmaceutische Wetenschappen Maddalena Centanni is dit jaar de winnaar van de Arenberg-Coimbragroep-Prijs voor Erasmusstudenten. Centanni bracht voor haar Erasmus-uitwisseling zes maanden door in Uppsala, Zweden. Hier onderzocht ze manieren om de dosering van anti-kankermedicijnen…
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
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Molecular characterization of copper-dependent enzymes involved in Streptomyces morphology
Promotor: G.P. van Wezel, Co-promotor: D. Claessen
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Towards near-infrared light-activated combination chemotherapy
The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.
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Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Save the date voor het FIDE XXIX Congres 20-23 mei 2020 – Den Haag
Na bijna veertig jaar keert het tweejaarlijkse congres van de Internationale Federatie van Europees Recht (FIDE) terug naar Nederland!
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Harnessing the immunostimulatory properties of oncolytic reovirus for anticancer immunotherapy
Promotie
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Student-for-a-Day Population Health Management
Studievoorlichting
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Student-for-a-Day Population Health Management
Studievoorlichting
- Save the date: 450-talk
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
- Save the date: Algemene ledenvergadering en lezing
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Student for a Day at International Relations and Organisations
Studievoorlichting
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Student for a Day at International Relations and Organisations
Studievoorlichting
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Student for a Day at International Relations and Organisations
Studievoorlichting
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Student for a Day at International Relations and Organisations
Studievoorlichting
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Urbanism and municipal administration in Roman North Africa
This project uses archaeological, literary and epigraphic evidence to investigate urban development in Roman-period North Africa, compiling this in a GIS-linked database in order to analyse the development of urban settlement spatially over time.
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Nanodeeltjes en licht gaan de strijd aan met kanker
De Leidse promovendus Xuequan Zhou heeft een veelbelovend nieuw molecuul ontworpen dat effectief kankercellen kan bestrijden zonder hierbij ook de gezonde cellen aan te tasten. De truc: het medicijn wordt pas actief als je het bestraalt met licht. Zhou’s nieuwe molecuul is extra efficiënt, aangezien…