Promotores: R. Tijdeman, K.J. Batenburg

Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

De wereld van vroegmodern Europa barstte van de spionage en geheime operaties. Hoogleraar Nadine Akkerman en Pete Langman onthullen de Engelse spionagetechnieken van de zestiende en zeventiende eeuw in hun boek: Spycraft: Tricks and Tools of the Dangerous Trade from Elizabeth I to the Restoration.

The Keuzegids Universiteiten 2015 (Guide for Study Choice Universities) has awarded Leiden University with five ‘Top Rated Programmes’: Mathematics, Biomedical Sciences, Greek and Latin Language and Culture, Liberal Arts & Sciences: Global Challenges and Philosophy.

De NWO heeft een Rubicon-beurs toegekend aan Sara Polak. Per september zal zij 12 maanden onderzoek doen bij het International Graduate Centre for the Study of Culture aan de Justus-Liebig Universität in Giessen, Duitsland.

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Dynamical systems describe the evolution of objects in a space over time and may be used to model physical phenomena. Due to this, much research is dedicated to understanding the mathematics of dynamical systems.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

Promotor: Prof.dr. M.A.G.J. Orrit

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

Promotor: Prof.dr. G.R. de Snoo

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

Promotores: W. Jiskoot, F. Ossendorp

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Bij LUC The Hague stel je je eigen curriculum (vakkenpakket) samen rond de afstudeerrichting van jouw keuze: je major. Een centraal thema in de studie blijft Global Challenges; in iedere major houd je je bezig met uitdagingen in de echte wereld, en je leert hoe je deze beter kunt begrijpen.

Kiemproject: Hoe kunnen metaforen bijdragen aan betere maatschappelijke betrokkenheid bij quantumwetenschap en -technologie, en welke factoren beïnvloeden de acceptatie of weerstand tegen metaforen bij zowel experts als leken?

De Leidse studenten Judith Zoetelief en Cartharine Wilson staan op de tweede en derde plaats bij de verkiezing van de beste master thesis over Afrika. Deze wereldwijde competitie van het Africa Studie Centrum telde 35 inzendingen. De prijsuitreiking is tijdens de Afrikadag op 17 november.

Gloria Moorman, masterstudent Book and Digital Media Studies, heeft met haar masterscriptie over de Italiaanse stedenatlas van Johan Blaeu's de Elsevier/Johan de Witt-scriptieprijs gewonnen. Joris Gerritse, student Geschiedenis aan de Universiteit Leiden, won met zijn bachelorscriptie de aanmoedigin…

Sinds 2009 behaalden 91 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.

This volume, edited by Kay Boers, Becca Grose (University of St Andrews), Rebecca Usherwood (Trinity College Dublin) and Guy Walker (Trinity College Dublin), brings together eight essays by eminent scholars and early career researchers, reflecting on the phenomenon of erasure in Late Antiquity (c. 150…

Afgestudeerden van de bachelor Security Studies aan de Universiteit Leiden hebben toegang tot diverse masterprogramma's en uitstekende carrièrekansen. Ontwikkel je als beveiligingsstrateeg en vergroot je kansen op een succesvolle carrière in zowel de publieke als private sector.

Grensverleggend geschiedenis leren.

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

How did colonial law work to turn people into property? This project argues that colonial ideas about households and domestic authority were critical to legal processes of enslavement in the early modern Dutch empire. Using colonial court records from Dutch Brazil, Suriname, and the Moluccas, the project…

Terugblik over de laatste 40 jaar op de belangrijkste veranderingen in de zorg en onderzoek, waar transparantie, verantwoording en richtlijn centraal zijn komen te staan. Aan de hand van de ziekte van Huntington en het cerebrovasculaire accident worden belangrijke veranderingen in de zorg en het onderzoek…

Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

This thesis investigates the structural evolution and assembly of galaxies since the first few billions years after the big bang.

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)

Lezing

Kennis van moslimsamenlevingen is onmisbaar om in een geglobaliseerde wereld te kunnen functioneren en om onze eigen Nederlandse maatschappij goed te begrijpen. In Leiden verdiepen onderzoekers zich in de talen, cultuur, religie, rechtssystemen en geschiedenis van moslimsamenlevingen en zetten daarmee…