Grensverleggend geschiedenis leren.

eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?

Berichtendienst Telegram komt steeds vaker negatief in het nieuws. Dit vanwege de criminele activiteiten die op het platform plaatsvinden. De actualiteitenrubriek EenVandaag van AVROTROS beantwoordt vragen van kijkers, luisteraars en lezers.

Voordrachten in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus (aug. 2017 – dec. 2023).

Cursus

This thesis describes the design, characterization and application of dextran based crosslinked network.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Tin electrodeposition applications have rapidly evolved in the past 25 years.

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

This research delves into a region of space known as the interstellar medium (ISM), which is essentially the area between the stars filled with gas and dust.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Het onderzoek in de cluster Algebra, meetkunde en getaltheorie slaat bruggen tussen abstracte theorie en de wereld van algoritmen en toepassingen.

Promotor: A. Kros

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

Patterned detectors are an existing technology that can be found in almost all color cameras.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

Enzymes are innately sensitive to changes in the amino acid sequence, which largely constrains their evolutionary potential, i.e., evolvability. This evolutionary burden can be alleviated in the presence of stabilizing mutations, which increase the buffering capacity of enzymes to tolerate mutations…

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.