Planets are formed in disks of gas and dust around young stars.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

Promotores: Prof.dr. G.F.A. Kersten, W. Jiskoot, Co-promotor: J-P. Amorij

This thesis investigates opinion dynamics on random graphs through the lens of the voter model, a classical interacting particle system used to describe how consensus emerges in networks.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

Climate change is one of the largest challenges faced by humanity. To combat this research into alternatives to fossil fuels is ongoing. Dihydrogen is considered a good alternative fuel, since its burning only forms water.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Food waste is a defining inefficiency of the modern food system, with profound implications for resource use, climate change, and circular economy transitions. This dissertation examines food waste through two complementary lenses: the prevention of avoidable food waste and the valorization of unavoidable…

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

This thesis addresses the challenge of sustainable urban development by analyzing the interplay between green and grey infrastructure to optimize resource use and ecosystem services.

The global transition toward low-carbon energy systems and the rapid expansion of digital technologies, including artificial intelligence, are reshaping how modern societies produce, move, and process energy and information.

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

This thesis aims to develop model-based approaches to optimize drug dosing in patients with overweight and (morbid) obesity.

In this thesis the links between allergy and intestinal health, the gut microbiome (GM), and external factors were studied by exploring the metabolome in longitudinal clinical studies and in vitro models.

The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

The global agri-food system plays a critical role in food security and environmental issues.

Promotores: G.A. Persoon, H.H. de Iongh

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska

Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra

This thesis surveys the intersection of computed tomography (CT) and machine learning (ML), treating CT as an ill-posed inverse problem shaped by object properties, imaging physics, and data limitations.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Als mensen of dieren meerdere beslissingen achter elkaar moeten nemen herhalen ze vaak systematisch hun keuzes of wisselen deze af - zelfs als de keuzes die ze maken intrinsiek ongecorreleerd zijn. Dit gedragspatroon (ook bekend als 'sequentieel effect' of 'keuzehysterese') is al minstens een eeuw bekend…

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

The zoo of detected exoplanets reveals both the uniqueness of our own Solar System and the complexity of planetary system formation, sparking fundamental questions about how planetary systems form and evolve.

Congres/symposium

Workshop

Promotie

In samenwerking met

Je kunt aan de Universiteit Leiden Kunstmatige Intelligentie studeren, maar ook binnen andere opleidingen speelt het een steeds grotere rol.

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

This thesis focuses on addressing four research problems in designing embedded streaming systems.

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

In this study, we investigated the electrochemical behavior and surface evolution of Au(111) electrode under different conditions and electrochemical techniques, using a homemade electrochemical scanning tunneling microscope (EC-STM), revealing the intricate interplay between surface roughening, atom…

Het onderwijs aan het Instituut Bestuurskunde richt zich op de brede studie van het openbaar bestuur, inclusief de semipublieke sector, lobbyorganisaties, het maatschappelijk middenveld en relevante private organisaties.

In this thesis, we investigate how deep generative models (AI models that can create new designs) can be better utilized for technical and industrial design. Our goal is to generate designs that are not only realistic (plausible), but also efficient, reliable, and usable in complex 2D and 3D applica…

Drug development is hampered by the limited predictive value of conventional 2D culture systems, which fail to recapitulate the complexity of the disease microenvironment and contribute to high clinical attrition rates.

Promotie

Promotie

Urbanisation is steadily increasing with estimates expecting that 68% of the global population will live in cities by 2050. To accommodate the rural to urban transition, large quantities of land are transformed from natural to urban lands.

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

Hoe overheden met maatschappelijke organisaties omgaan en hoe maatschappelijke organisaties publieke besluitvorming kunnen beïnvloeden en hun organiserend vermogen staan centraal binnen dit onderzoeksprogramma. Als zodanig biedt dit onderzoeksprogramma, en de leerstoel waaraan het verbonden is, unieke…

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?