Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

‘Over leven in Aarlanderveen’ ,de film die masterstudent Marleen Oostenrijk voor haar afstudeerproject van Culturele Antropologie en Ontwikkelingssociologie maakte, wordt 22-28 februari uitgezonden door Studio Alphen. De film brengt de leefbaarheid in beeld van het dorp en wat leefbaarheid inhoudt…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Culturele Antropologie en Ontwikkelingssociologie in Leiden staat bekend om haar internationaal georiënteerde expertise. Met een breed scala aan theoretische, methodologische en regionale onderwerpen, biedt de opleiding een sterk gefundeerd en verdiepend programma.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Indigenous Latin American artifacts have attracted the interest of Europeans since the earliest moment of contact between Europeans and the Indigenous peoples of the Americas. The ERC-funded BECACO project uses an innovative multidisciplinary framework to investigate the provenance of ethnographic and…

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Vanaf de koloniale tijd tot heden hebben grote aantallen Javanen hun woonplaats verlaten om zich in andere delen van Indonesië of veel verder weg te vestigen. Vaak was deze spreiding gedwongen, vaak met traumatische gevolgen.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Lezing, SMILE Talks

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

This dissertation presents new cryptographic protocols, which can be divided into two families.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Dit project bekijkt het Oudgrieks vanuit het perspectief van de alledaagse schrijvers. Een corpus van meer dan 60.000 Griekse teksten op papyrus, van privébrieven tot petities en contracten geeft ons toegang tot de Griekse taal zoals die werd geschreven door gewone mensen in de oudheid (van 300 v.Chr.…

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Het WARN-project heeft als doel te begrijpen waarom sommige waarschuwingen niet effectief genoeg zijn of niet tijdig de juiste besluitvormers bereiken om een crisis af te wenden.

Promotores: G. Persoon, R. Schefold

The global agri-food system plays a critical role in food security and environmental issues.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Hoewel deze twee disciplines ooit gescheiden paden bewandelden, zijn ze tegenwoordig nauw met elkaar verbonden. In dit artikel bespreken we wat beide vakgebieden precies inhouden, waarin ze elkaar overlappen en waar ze van elkaar verschillen.

Benieuwd of bachelor opleiding Cultural Anthropology and Development Sociology van Universiteit Leiden bij je past? Bekijk de opleidingsvideo.

Een kenniswerkplaats is een samenwerkingsverband tussen verschillende organisaties, zoals scholen, onderzoeksinstellingen en beleidsmakers. Het doel is om gezamenlijk praktijkgericht onderzoek uit te voeren om kennis te ontwikkelen en beschikbaar te maken voor de praktijk.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Dit artikel gaat in op de onderzoekskloof door te onderzoeken hoe deze instanties hun personeel zo kunnen inzetten dat ze maximale prestaties leveren met het personeel dat ze hebben.