287 zoekresultaten voor “final beyond” in de Publieke website
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Unconventional fabrication of 2D nanostructures and graphene edges
In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.
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Current challenges in statistical DNA evidence evaluation
Promotor: R.D. Gill, F. Taroni
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Patterned detectors: From design to science
Patterned detectors are an existing technology that can be found in almost all color cameras.
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Magnetism and magnetization dynamics in thin film ferromagnets
Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek
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Fostering Curiosity Through Video Games
This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.
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The potential of multi-scale EE-MRIO to support sustainable development policies in Indonesia
Global Environmental Extensions Multi-Regional Input-Output (EE-MRIO) analysis is often used to analyze how changes in global and national demand for products lead to socioeconomic and environmental impacts at the national level.
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Nuclear magnetic resonance force microscopy at millikelvin temperatures
Promotor: T.H. Oosterkamp
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Computational modeling of angiogenesis : from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Geometric approach to evolution problems in metric spaces
Promotor: S.M. Verduyn Lunel, Co-promotor: O.W. van Gaans
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli
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Miniaturized metabolomics methods for enabling the study of biomass- restricted samples
This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.
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Exploring the chemical space of natural products from Streptomyces using multi-omics approaches
The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Dynamics and regulation of the oxidative stress response upon chemical exposure
The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Dynamical Gibbs-non-Gibbs transitions and Brownian percolation
Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.
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Computational speedups and learning separations in quantum machine learning
This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…
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From pixels to patterns: AI-driven image analysis in multiple domains
This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.
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Counting problems for number rings
Promotor: H.W. Lenstra
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Het miljard deeltjes probleem
Promotor: Prof.dr. S. Portegies Zwart
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Taxonomic and Paleobiological insights into Small Mammals from the Pliocene of Western Turkey
The thesis explores micromammal fossils from the Afşar section in Anatolia, a crucial locality for understanding the Pliocene epoch and the transition to the Villafranchian Age.
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PLGA-based particulate vaccine delivery systems for immunotherapy of cancer
Promotores: W. Jiskoot, F. Ossendorp
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Tracing life through light: Towards detecting life on exoplanets with spectroscopy and spectropolarimetry
How did we come into existence? Are we alone? These questions have driven humans for centuries.
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The unexplored functions of Toll-like receptor signaling: Immunometabolism, development and microbiome interactions
Toll-like receptors (TLRs) are central components of the innate immune system, functioning as pattern recognition receptors that detect microbial- and damage-associated molecular patterns and initiate antimicrobial and inflammatory responses.
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History (MA)
De master History van de Universiteit Leiden heeft een sterk internationaal karakter en focust op Europese- en niet-Europese geschiedenis vanuit een globale context.
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Literary Studies (MA)
De master Literary Studies van de Universiteit Leiden biedt een gespecialiseerde kwalificatie in één van vier talen (Engels, Frans, Duits en Italiaans) en culturen, of een vergelijkend perspectief op literatuur en cultuur. Elk programma biedt veel ruimte voor individuele keuzes.
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Species Literacy: The perception and cultural portrayal of animals
In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Multi-objective mixed-integer evolutionary algorithms for building spatial design
Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.
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Identifying the origins of galaxy formation
This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.
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Strategies for Mechanical Metamaterial Design
On a structural level, the properties featured by a majority of mechanical metamaterials can be ascribed to the finite number of soft internal degrees-of freedom allowing for low-energy deformations.
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Over de grens van de onrechtmatige daad
Op 12 januari 2022 verdedigde Mirjam Franke het proefschrift 'Over de grens van de onrechtmatige daad'. Het promotieonderzoek is begeleid door prof.mr. A.G. Castermans en prof.mr. J.H. Crijns.
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Artificiele Intelligentie en Ethiek bij de Politie
Artificiele Intelligentie en Ethiek bij de Politie
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Natural Product Antibiotics: Synthesis and Next Generation Analogues
This thesis addresses the urgent challenge of antimicrobial resistance through the discovery and modification of natural product antibiotics.
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Model-informed Design of Antibiotic Therapy against Antimicrobial Resistance
Antibiotic resistance is a growing global health threat, while the development of new antibiotics has slowed.
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Immunotherapy for metastatic melanoma and beyond
Promotie
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Mensenrechten en klimaatverandering
Het is moeilijk om de waarde en het belang van mensenrechten te ontkennen, en toch wordt hun toepassing in de context van klimaatverandering steeds meer betwist. Terwijl sommigen beweren dat het moeilijk is om de schending van mensenrechten door klimaatveranderingsprocessen vast te stellen, beweren…
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Plan B for particle physics: finding long lived particles at CERN
This thesis discusses the discovery potential of Intensity Frontier experiments.
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Transformaties in de mondiale klimaatfinanciering
Klimaatfinanciering, vooral voor ontwikkelingslanden, is van cruciaal belang om de opwarming van de aarde tot 1,5 graden Celsius te beperken. Het huidige niveau van de Noord-Zuid-klimaatfinanciering is echter chronisch ontoereikend. Naarmate de klimaatcrisis heviger wordt, betreden steeds meer actoren…
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Topological phases and phase transitions in magnets and ice
The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.
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Partnerships
The AI Collaboration Centre focuses on delivering Smart Computing for Science & Industry. This is reflected in our long-term collaborations with industry and government partners. These partnerships keep our research grounded in real-world applicability while opening new directions within computer sc…
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Uniform infinite and Gibbs causal triangulations
Promotor: Richard D. Gill
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Special edition Information Polity
In this special edition of Information Polity there is a focus on the transparency challenges of using algorithms in government in decision-making procedures at the macro-, meso-, and micro-levels.