Abstract submission is now open for the international conference of the ELS Academy, in Amsterdam on September 1 and 2. For the 2022 International ELS Conference, we invite all involved in legal research using qualitative and/or quantitative methods to submit abstracts, that may focus on ongoing or…

Op 7 mei 2020 verdedigde Jolanda van der Vliet proefschrift 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.J. Schrijver en prof.dr.ir. J.J.C. Voorhoeve.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Effective policy-making requires understanding what truly causes a problem. Only then can policymakers develop targeted interventions that achieve desired outcomes.

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

Vanaf 1 april is Rowie Stolk vanuit de afdeling Staats- en bestuursrecht voor 0,7 fte verbonden aan Empirical Legal Studies Leiden (ELS@Leiden). ELS biedt een platform om juristen en sociaalwetenschappers bij elkaar te brengen om tezamen juridische vragen te onderzoeken. Er wordt gebruikgemaakt van…

Recently, a new edition of the ELS bulletin was sent out. Furthermore, we are thrilled to share the Midterm Report of the ELS lab @Leiden with you!

Patterned detectors are an existing technology that can be found in almost all color cameras.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

This thesis advances automata learning, a key area in computer science, with applications in software verification, biological analysis, and autonomous technologies. It explores three main themes: first, it introduces a passive learning algorithm for generating compact probabilistic models from positive…

Op 26 mei 2016 is tijdens de 5e ‘Dutch Legal Tech Meetup’ de Legal Tech Denktank gelanceerd. De leden van de Denktank zijn verbonden aan Kennedy van der Laan, Dutch Legal Tech, Wolters Kluwer en Universiteit Leiden. De Denktank ziet toe op het geven van een inhoudelijke verdieping van technologie-gedreven…

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

In het hoger onderwijs zijn open leermaterialen beschikbaar die iedereen mag gebruiken, maar ze worden niet zo veel gebruikt.

Het onderzoek richt zich op de vraag hoe op gemeentelijk niveau wordt omgegaan met klachten over jeugdhulp in het vrijwillige kader en welke rol (gemeentelijke) Kinderombudsmannen hierin spelen, door middel van kwalitatief onderzoek.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

How can data analytics be used as a research method in the field of legal research? This question was addressed during the Research Lab Legal Data Science on 23 September, 2016.

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

Op 7 november 2018 verdedigde Catherine Harwood haar proefschrift 'Navigating Between Principle and Pragmatism: The Roles and Functions of Atrocity-Related United Nations Commissions of Inquiry in the International Legal Order'. Het promotieonderzoek is begeleid door promotoren prof. dr. L.J. Van den…

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

The cellular metabolism of immune cells constitutes an important part of their proper function and activation. Using T cells as an example, this phenomenon is highlighted by the metabolic reprogramming that occurs in these cells upon activation.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Wednesday 16 November 2016, 12.30-14.00

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…

Promotor: Prof.dr. M. Ubbink

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.