2,724 zoekresultaten voor “state cell technology” in de Publieke website
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hydrogels as synthetic extracellular matrices for three- dimensional cell culture
Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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The aging B cell landscape in atherosclerosis
Promotie
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Terpenoids and terpenoid indole alkaloids in Catharanthus roseus cell suspension cultures
Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte
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Establishing State Responsibility in the Absence of Effective Government
Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).
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Towards in-cell structural study of light-harvesting complexes : an investigation with MAS-NMR
Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Connecting dots between natural and artificial Photosynthesis
Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.
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Quantitative live cell imaging of glucocorticoid receptor dynamics in the nucleus
In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.
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State-resolved studies of CO2 gas-surface reactions
The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.
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Visual analytics for spatially-resolved omics data at single cell resolution: Methods and Applications
The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…
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Leiden Genome Technology Center
De faciltieit ontwikkelt en gebruikt, high-throughputmethoden toe voor genomisch onderzoek.
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Maak kennis met de opleiding Life Science and Technology
Hoe kun je virussen als medicijn laten werken? Hoe kunnen bacteriën schadelijke stoffen in het milieu afbreken? Hoe worden algen omgevormd tot producenten van biobrandstof? Dit zijn typische vragen die je bij de opleiding LST behandelt. Je combineert de vakgebieden wiskunde, scheikunde, natuurkunde…
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Maak kennis met de opleiding Life Science and Technology
Hoe kun je virussen als medicijn laten werken? Hoe kunnen bacteriën schadelijke stoffen in het milieu afbreken? Hoe worden algen omgevormd tot producenten van biobrandstof? Dit zijn typische vragen die je bij de opleiding LST behandelt. Je combineert de vakgebieden wiskunde, scheikunde, natuurkunde…
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Nieuw handboek “EU State Aids”
Het doet het Europa Instituut genoegen aan te kondigen dat op 21 november 2016 de 5e druk is verschenen van het handboek “EU State Aids” (31 hoofdstukken, 1500 pagina’s).
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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Operando Spectro-electrochemical investigations of Pt and Pt-alloys as Fuel Cell Catalysts
The overall theme of this thesis is to complement the electrochemical data acquired in fuel cell research with in situ X-ray photoelectron spectroscopy (XPS) and soft X-ray absorption spectroscopy (XAS).
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Macrophage cell models for the investigation of Gaucher disease
Promotie
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Quantum dots in microcavities: From single spins to engineered quantum states of light
A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…
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Public Health and the American State
Dit boek onderzoekt hoe zorgen over de volksgezondheid en politieke agenda’s elkaar in de VS de afgelopen eeuw hebben beïnvloed.
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Bridging the Gap Between Design and Implementation for Technology-Enhanced Learning Systems
Technologies that help to enhance our educational environments can be found everywhere.
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Life cycle assessment of emerging chemical technology systems: challenges and future needs
The upscaling of Life Cycle Assessment (LCA) data is recognized as one of the main challenges in the ex-ante LCA of emerging technologies. This challenge arises since industrial-scale system specifications for these technologies are unknown and industrial data is lacking.
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informality of the international cybersecurity regime: Geopolitics, non-state actors and diplomacy
De auteurs analyseren twee belangrijke factoren die informaliteit verdiepen, namelijk multipolaire geopolitiek en de opkomst van niet-statelijke actoren.
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Cyber agent technology en de Wet op de Inlichtingen- en Veiligheidsdiensten (WIV)
Onderzoek uitgevoerd door eLaw, centrum voor recht en digitale technologie Universiteit Leiden in opdracht van Tracks Inspector Den Haag.
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Strategies for braiding and ground state preparation in digital quantum hardware
With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.
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Image-based phenotypic screening for breast cancer metastasis drug target discovery
The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.
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Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Foreign intelligence in the digital age. Navigating a state of 'unpeace'.
Het The Hague Program for Cyber Norms, een onderzoeksprogramma van het Institute of Security and Global Affairs, heeft zijn eerste beleidsnota gepubliceerd. Hierin onderzoeken Dennis Broeders, Sergei Boeke en Ilina Georgieva de rol van inlichtingendiensten in cyberspace en de (on)mogelijkheden van adequate…
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Let Them Roar: Small States as Cyber Norm Entrepreneurs
Sinds de United Nations Group of Governmental Experts on the Developments in the Field of Information and Telecommunications in the Context of International Security (UN GGE) elf aanbevelingen heeft gedaan over verantwoordelijk staatsgedrag omtrent cyberspace is er een discussie gaande over internationale…
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Domestic Courts in Investor-State Arbitration: Partners, Suspects, Competitors
Op 27 juni 2019 verdedigde Vid Prislan zijn proefschrift 'Domestic Courts in Investor-State Arbitration: Partners, Suspects, Competitors'. Het promotieonderzoek is begeleid door promotor prof. dr. N.J. Schrijver.
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State Silence and the International Law of Cyberspace
This article offers an inaugural assessment of how silences implicate international law-making in cyberspace through descriptive and normative lenses.
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States in shock: De aanpassingscapaciteiten van staatsadministraties bij grensoverschrijdende crises
Deze studie onderzoekt hoe Europese staatsadministraties de afgelopen 30 jaar hebben gereageerd op grensoverschrijdende crises en in hoeverre zij succesvol zijn aangepast.
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Catecholamine function, brain state dynamics, and human cognition
Het onderzoek in dit proefschrift kijkt naar de rol van het locus ceuruleus - noradrenalinesysteem in verscheidene aspecten van menselijke cognitie, en de modulatie van de staat van het brein.
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Cel analyseren op atoomniveau met Cell Observatory
Details kunnen zien van een zieke of gezonde cel, dat is mogelijk met de supermicroscoop van het consortium Cyttron. Niet alleen de microscoop is vernieuwend in zijn soort: ook de vorm waarop de partijen samenwerken past in de huidige tijd. “Toegang tot elkaars techniek, daar draait het om in ons samenwerkingsverband”,…
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Cell Observatory en labs voorzichtig van start
Met de nodige maatregelen starten onderzoekers hun werkzaamheden in verschillende laboratoria weer deels op. Het Leidse Cell Observatory is één van de plekken waar wetenschappers sinds 11 mei hun labwerk hervatten.
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Tien jaar Life Science and Technology
Op 9 september 2009 viert de opleiding Life Science and Technology (LS&T) haar tienjarig bestaan.
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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Raad van State in de schijnwerpers: zorgen over politieke betrokkenheid
De onafhankelijkheid van de Raad van State staat onder druk door recente uitspraken van staatsraad Richard van Zwol, stelt Annemarie Kok in NRC.
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Luc Verhey wordt lid van de Raad van State
Luc Verheij hoogleraar Staats en bestuursrecht (Kircheiner-leerstoel) in Leiden wordt lid van de Raad van State. Sinds 2011 is Verheij al staatsraad in de Afdeling advisering. Deze rol blijft hij vervullen en wordt daarnaast ook lid van deze Raad.
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Synthesis of phosphodiester-containing bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Identification and characterization of developmental genes in streptomyces
Promotor: Prof.dr. G.P. van Wezel
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Characterization of age-associated immunity in atherosclerosis
Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…
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Mast cells in advanced atherosclerosis: from human plaque stability to new therapeutic targets
In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.
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Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace
Op 10 juni 2021 verdedigde Merinda Stewart haar proefschrift 'Freedom of Overflight: A Study of Coastal State Jurisdiction in International Airspace'. Het promotieonderzoek is begeleid door promotoren prof.dr. P.M.J. Mendes de Leon en prof.dr. J.J. Rijpma.
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Rebel Legal Order, Governance and Legitimacy: Examining the Islamic State and the Taliban Insurgency
Dit artikel onderzoekt hoe ISIS en de Taliban steun hebben gekregen door hun parallelle rechtssystemen.
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Borders in Dispute: The Construction of State and Nation in International Diplomacy
How are borders drawn? More specifically, how do diplomatic actors manage the implications of changes in state sovereignty for international borders?
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Into the ether or the state? Legibility theory and the cryptocurrency markets
In dit artikel presenteren Kellerman en Seddon een nieuw conceptueel kader waarin het concept van marktleesbaarheid centraal staat.