This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

Op 14 december 2016 verzorgde Steven L. Schwarcz, Stanley A. Star Professor of Law & Business aan Duke University School of Law de dertiende Hazelhoff Guest Lecture. Voorafgaand aan deze lezing organiseerde het Hazelhoff Centre for Financial Law een rondetafelgesprek met Professor Schwarcz en personen…

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

Patterned detectors are an existing technology that can be found in almost all color cameras.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

This thesis advances automata learning, a key area in computer science, with applications in software verification, biological analysis, and autonomous technologies. It explores three main themes: first, it introduces a passive learning algorithm for generating compact probabilistic models from positive…

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Van deepfakes en disinformatie tot killer robots, chirurgische robots en AI wetgeving: AI (Artificial Intelligence, kunstmatige intelligentie) verandert onze wereld. Dat roept de vraag op of enige vorm van regulering nodig is. Bij eLaw, het centrum voor recht en digitale technologie van de Universiteit…

In het hoger onderwijs zijn open leermaterialen beschikbaar die iedereen mag gebruiken, maar ze worden niet zo veel gebruikt.

Het onderzoek richt zich op de vraag hoe op gemeentelijk niveau wordt omgegaan met klachten over jeugdhulp in het vrijwillige kader en welke rol (gemeentelijke) Kinderombudsmannen hierin spelen, door middel van kwalitatief onderzoek.

Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…

Promotor: Prof.dr. M. Ubbink

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

This article offers an inaugural assessment of how silences implicate international law-making in cyberspace through descriptive and normative lenses.

The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds.

In this article, Eamon Aloyo argues that university supervisors should not use student evaluations of teachers as a measure of teaching effectiveness.

Dit artikel beoordeelt de Russische retoriek ten aanzien van Oekraïne door verklaringen van het Russische ministerie van Buitenlandse Zaken te analyseren.

Dit artikel geeft antwoord op de vraag: Hoe kunnen we de ontwikkeling van eco-labels gestructureerder en transparanter maken?

Dit artikel introduceert een nieuwe dyadische benadering om stemgedrag in de Raad van de Europese Unie te bestuderen.

Dit artikel geeft een overzicht van de literatuur over de effecten van multilevel governance (MLG) op de beleidsreacties van regeringen op Covid-19.

In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Het middelbaar beroepsonderwijs (mbo) wordt gekenmerkt door drie belangrijke componenten: het leren op school, het leren op de werkplek en de verbinding daartussen. Reflectievaardigheden spelen een belangrijke rol bij die verbinding.