808 zoekresultaten voor “a guest depression” in de Publieke website
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A monograph of the plant genus Trigonostemon Blume
Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.
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Minor Creative Strategies for a Society in Change
De minor Creative Strategies for a Society in Change (CSSC) legt een verbinding tussen het verkrijgen van inzicht in creatieve maakprocessen en het verkennen van maatschappelijke problematieken die kenmerkend zijn voor onze tijd.
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Hoop Dance: the hoop as a tool for expression
Kunst en vrije tijd, Kunst en vrije tijd
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Cavities for light and sound: a cavity-enhanced platform for quantum acoustics
Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Conversation with Dr Graça Machel: intergenerational justice from a human rights perspective
Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…
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Untangling cosmic collisions: a study of particle acceleration and magnetic fields in merging galaxy clusters
On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.
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Probing the Limits of Quantum Mechanics using a Cold Mechanical Force Sensor
In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.
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resolving supramolecular packing of artificial antennae chromophores through a hybrid approach
Promotor: H.J.M. de Groot
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Suppressing a Sea of Starlight: Enabling technology for the direct imaging of exoplanets
Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Opportunity and Problem in Context (OPiC). A framework for environmental management in developing countries
Promotor: W.T. de Groot
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: Prof.dr. J.N. Kok
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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The Diving Dutchman: het marien-gravimetrisch onderzoek van F.A. Vening Meinesz (1887-1966)
Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra
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The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
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Resolving a bioindicator diatom species complex using genomic approaches for freshwater biomonitoring
This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Superlattices in van der Waals materials: A Low-Energy Electron Microscopy study
n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.
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Theory of mind in language, minds, and machines: a multidisciplinary approach
Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
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Balancing between pain relief and respiratory depression
Promotie
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Transport coefficients and low energy excitations of a strongly interacting holographic fluid
In this thesis, classes of strongly interacting quantum field theories, have been studied.
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Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
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Towards a Structural Understanding of Plant─Microbiota Interactions using cryo-EM Techniques
The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.
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A Feminine or Masculine Crisis? Gender Stereotypes and Leadership During a Pandemic
Kantorowicz onderzoekt hoe genderstereotypen de perceptie van leiderschapscompetentie beïnvloeden bij verschillende soorten crises.
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Developing a behavioural cybersecurity strategy: A five-step approach for organisations
Dit onderzoek presenteert een vijfstappenplan voor de ontwikkeling van een effectieve gedragsgerichte cyberveiligheidsstrategie.
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Weighting factors for LCA - A new set from a global survey
De auteurs presenteren een benadering voor het achterhalen van de voorkeuren van de bevolking voor gebruik in de optionele wegingstap in de Levenscyclusanalyse (LCA).
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From Crisis to Inquiry: A Framework for Designing and Assessing Crisis Inquiries from a Learning Perspective
In dit artikel onderzoeken Wout Broekema, Wouter Jong en Sara Perlstein het ontwerp en de beoordeling van crisisonderzoeken vanuit een leerperspectief.
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Coping with administrative tasks: A cross-country analysis from a street-level perspective
This study seeks to analyse how job stress could be the result of performing administrative tasks
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Functionalized two-dimensional membranes and materials for solar-to-fuel devices: a multiscale computational approach
In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.
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Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Picturing Intimacy: Mediation and Self-representation in a Boston’s Religious Festivals
Taking as a point of departure the Italian American community in Boston and its process of collective remembrance surrounding Saint Anthony’s Feast, we addressing the limits and potential of montage.
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CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Towards secure and sustainable supply chains: a multi-perspective risk assessment for photovoltaics
Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.
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Een master Political Science aan de Universiteit Leiden: online Q&A
Studievoorlichting
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Towards a single-molecule FRET study of Frauenfelder's nonexponential rebinding of CO in myoglobin
Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson
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Explicit Computation of the Height of a Gross-Schoen Cycle
Arithmetic geometry concerns the number-theoretic properties of geometric objects defined by polynomials. Mathematicians are interested in the rational solutions to these geometric objects.
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A chemical biology approach to explore lipid metabolism in neurological disorders
Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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The architects of crenarchaeal chromatin: A biophysical characterization of chromatin proteins from Sulfolobus solfataricus
Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame
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Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.