In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…

Promotor: Prof.dr. D. Bouwmeester, Co-Promotor: M.J.A. de Dood

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…

Scattering of light in the presence of nano-structured materials, i.e. with features in the order of the wavelength of the light or smaller, reveals details of how light interacts with matter at the nanoscale.

We are living in an information era where the amount of image and video data increases exponentially.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

Promotie

Promotores: R. Tijdeman, K.J. Batenburg

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.

Promotor: J. Aarts

Op 19 september 2019 verdedigde Lynette Janssen zijn proefschrift 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. Het promotieonderzoek is begeleid door promotoren prof.mr. W.A.K. Rank en prof.mr. M. Haentjens.

In dit artikel onderzoeken Malte Reimann en Antonio Cerella hoe politiek en geneeskunde nauw met elkaar verweven zijn geraakt. Ze gebruiken daarbij het gedachtegoed van Roberto Esposito om deze relatie opnieuw te bekijken vanuit het perspectief van een bevestigend biopolitiek.

Students with learning problems experience difficulties in reading, writing, and content-area learning into and throughout their secondary-school years

Dit artikel beschrijft het ontstaan van een app die kan helpen om het klimaatbewustzijn en de actie wereldwijd te vergroten.

This paper presents the prevalence and characteristics of firearm homicides in Denmark, Finland, the Netherlands, Sweden and Switzerland

Dit artikel onderzoekt aanmoediging door leiderschap en psychologische veiligheid als antecedenten van prosociaal regelovertredend gedrag (PSRB).

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Details kunnen zien van een zieke of gezonde cel, dat is mogelijk met de supermicroscoop van het consortium Cyttron. Niet alleen de microscoop is vernieuwend in zijn soort: ook de vorm waarop de partijen samenwerken past in de huidige tijd. “Toegang tot elkaars techniek, daar draait het om in ons samenwerkingsverband”,…

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Met de nodige maatregelen starten onderzoekers hun werkzaamheden in verschillende laboratoria weer deels op. Het Leidse Cell Observatory is één van de plekken waar wetenschappers sinds 11 mei hun labwerk hervatten.

Workshop

Workshop

The focus of this thesis is how stars like our Sun and planets like Jupiter, Saturn, and Earth are formed.

Promotor: Prof.dr. T. Schmidt

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

In this project, researchers from computer science, law, psychology, and public administration research in practice how artificial intelligence (AI) can be leveraged to make decision-making in the security domain more effective, while also keeping it safe and accountable.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

Op 21 oktober 2021 verdedigde Frederik Behre het proefschrift 'A European Ministry of Finance?'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Promotor: Prof.dr. R.M.H. Merks

In this thesis we use state-of-the-art observations and simulations to provide the best constraints to date on the HVS ejection rate and constraints on the stellar content and dynamics at the GC, including the progenitor binary populations and their star formation history.