We are living in an information era where the amount of image and video data increases exponentially.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

In this thesis we study products of linear error correcting codes.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…

De Faculteit Governance and Global Affairs introduceert met genoegen een nieuwe serie research seminars. Het FGGA Research Seminar zal een forum zijn voor de presentatie van en discussie over actueel hooggekwalificeerd onderzoek naar onderwerpen waar de faculteit zich mee bezig houdt.

De Stichting Intelligence Studies zoekt een bijzonder hoogleraar voor de leerstoel Governance of Intelligence and Security Services. De leerstoel is met ingang van 1 september 2017 gevestigd aan de Universiteit Leiden, Faculty of Governance and Global Affairs bij het Institute of Security and Global…

Europese burgers worden geconfronteerd met uitdagingen op het gebied van globalisering, migratie, technologische ontwikkelingen en klimaatverandering. Deze uitdagingen vergen het uiterste van onderlinge internationale en intergenerationele solidariteit, wat rechtstreeks betrekking heeft op de grondslagen…

LUC is the first to confer the diploma of the Faculty of Governance and Global Affairs, the new Faculty name since January 2016 making this graduation an extra special occasion.

From 3 to 5 September 2025, the project Governing and Building the City will organize the conference 'Good Governance and the Built Environment of Late Medieval Cities (ca. 1200–1600)' at KBR in Brussels. The deadline for the call for papers is 7 April.

In this special edition of Information Polity there is a focus on the transparency challenges of using algorithms in government in decision-making procedures at the macro-, meso-, and micro-levels.

Kunst en vrije tijd, Kunst en vrije tijd

In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

In this work, we attempt to answer the question:

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

Healthy aging is one of the prime goals in today's society and atherosclerosis is among the greatest causes of morbidity in elderly. Cardiovascular disease patients receiving treatment are often of advanced aged and have an aged immune system, which limits translating experimental findings to the pa…

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

Promotor: W. Jiskoot, Co-promotor: A. Hawe

Green hydrogen is produced via a process called water electrolysis. During electrolysis water is split into oxygen and hydrogen.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Op 7 december 2021 verdedigde Georgina Kuipers het proefschrift 'Beschadigd vertrouwen'. Het promotieonderzoek is begeleid door prof.mr. W. den Ouden en prof.dr. M.A. van der Steen (EUR).

The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.

Promotor: T. H. Oosterkamp

Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom

Hydrocarbonylation of alkenes with carboxylic acids in synthesis of carboxylic acid anhydrides is relatively less explored. We herein present a study and optimization of a palladium-catalyzed hydrocarbonylation reaction of alkenes using carboxylic acids as the nucleophile, by which acid anhydrides can…

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Promotores: T.H. Oosterkamp, N. de Jonge

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.