In this course, you will develop an understanding of evolutionary processes and their formative power. You will see how evolution has shaped biodiversity, and continuously influences our daily life.

Deze minor richt zich op de cognitieve processen die invloed hebben op de wisselwerking tussen brein en bewustzijn.

Aangezien jeuk en pijn zeer belastend kunnen zijn, vooral wanneer mensen chronisch aan (een van) deze symptomen lijden, is het belangrijk te weten door welke factoren deze gewaarwordingen worden beïnvloed. Het wordt steeds duidelijker dat psychologische factoren een belangrijke rol spelen bij het ervaren…

Het onderzoek van Anne Helder toont aan wat in het brein gebeurt als lezers een tekst lezen waarin iets staat dat niet klopt. Promotie 15 november.

Het begrijpen van individuele verschillen in zelfregulatie bij jongens met ODD/CD op het niveau van het brein, cognitie en gedrag

Consequences for sediment stability and seston trapping

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Planets are formed in disks of gas and dust around young stars.

Promotor: A. Kros

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

The applications of studying the early development of insects range from agriculture to material science.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Promotor: Prof.dr. R.M.H. Merks

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Promotor: Prof.dr. T. Schmidt

Cell-based medicinal products (CBMPs), such as CAR T cells, are highly complex biopharmaceutical products offering various treatment options for serious illnesses such as cancer or autoimmune diseases.

Humanity stands at a pivotal juncture, facing the dual challenge of environmental sustainability and rapid population growth, projected to exceed 11 billion by century’s end.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Promotor: Prof.dr. E.F. van Dishoeck

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Promotor: J.W.M. Frenken

Bent u ouder van een jongere (10-18 jaar) die een ingrijpende gebeurtenis heeft meegemaakt, zoals een ongeluk, geweld, misbruik of ernstig pesten? Voor een wetenschappelijk onderzoek van de Universiteit Leiden zijn prof. dr. Bernet Elzinga en promovenda Kyra Verboon (sectie Klinische Psychologie) op…

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

In deze master specialisatie ligt de focus op het begrijpen van biologische processen in hun natuurlijke context, zoals cellen en weefsels.