Deze serie benadert begrijpend lezen vanuit een cognitief perspectief. We beschrijven hoe lezers tot begrip komen. Dat wil zeggen: hoe zij coherente mentale representaties opbouwen tijdens het lezen van tekst.

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

Promotor: G. J. Kroes

If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Al het onderzoek van de Universiteit Leiden is georganiseerd in instituten. Om recht te doen aan de veelkleurigheid van het onderzoek (en dus ook aan het onderwijs) dat daar uit voortvloeit vindt u op deze pagina’s omschrijvingen van alle Leidse instituten.

Het onderzoek van de programmagroep Onderwijswetenschappen richt zich op ‘het lerende kind in het onderwijs’. De focus ligt op processen die plaatsvinden tijdens de ontwikkeling en het leren.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

The development process of any software has become extremely important not just in the IT industry, but in almost every business or domain of research.

Bepaalde ontwikkelingsfases en specifieke problemen van kinderen, zoals somberheid en angsten, vragen om specifieke benaderingen, waar ouders steeds opnieuw vorm aan moeten geven. Hoe wordt onderzoek naar ouderschap en de invloed hiervan op het welzijn van kinderen vormgegeven, en wat valt hiervan te…

This thesis focuses on addressing four research problems in designing embedded streaming systems.

In this course, you will develop an understanding of evolutionary processes and their formative power. You will see how evolution has shaped biodiversity, and continuously influences our daily life.

Deze minor richt zich op de cognitieve processen die invloed hebben op de wisselwerking tussen brein en bewustzijn.

Aangezien jeuk en pijn zeer belastend kunnen zijn, vooral wanneer mensen chronisch aan (een van) deze symptomen lijden, is het belangrijk te weten door welke factoren deze gewaarwordingen worden beïnvloed. Het wordt steeds duidelijker dat psychologische factoren een belangrijke rol spelen bij het ervaren…

Wat is emotie in menselijke en niet-menselijke dieren? Hoe worden emoties uitgedrukt en hoe beïnvloeden ze onze interacties, onze beslissing om te vertrouwen, te wantrouwen en mee te werken? Waarom imiteren en synchroniseren we affectieve processen?

Arco Timmermans, Bijzonder Hoogleraar Public Affairs aan het Instituut Bestuurskunde, besprak bij EenVandaag de opvallende verandering in het in juni gepubliceerde GGD-rapport over kanker rond Beverwijk.

Het onderzoek van Anne Helder toont aan wat in het brein gebeurt als lezers een tekst lezen waarin iets staat dat niet klopt. Promotie 15 november.

Cell-based medicinal products (CBMPs), such as CAR T cells, are highly complex biopharmaceutical products offering various treatment options for serious illnesses such as cancer or autoimmune diseases.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Het begrijpen van individuele verschillen in zelfregulatie bij jongens met ODD/CD op het niveau van het brein, cognitie en gedrag

In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.

Promotor: A. Kros

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.

Planets are formed in disks of gas and dust around young stars.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Promotor: G.R. de Snoo, Co-promotor: C.J.M. Muster

Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Promotor: Prof.dr. E.F. van Dishoeck

Promotor: J.W.M. Frenken

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

Consequences for sediment stability and seston trapping

The applications of studying the early development of insects range from agriculture to material science.

Humanity stands at a pivotal juncture, facing the dual challenge of environmental sustainability and rapid population growth, projected to exceed 11 billion by century’s end.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Promotor: Prof.dr. T. Schmidt

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).