In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

The impact of the phenotypic plasticity of P. aeruginosa and the distinct CF lung microenvironments on antibiotic drug effects and resistance remains poorly understood.

Kunst en vrije tijd, Kunst en vrije tijd

Did the Jochids leave their mark on the Grand Duchy, taking into account that the Lithuanian state was one of the main successor states of the Great Horde in the 16thCentury?

The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…

This thesis focuses on the design and synthesis of activity-based probes and inhibitors targeting enzymes involved in the degradation of specific plant glycans.

Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

The goal of this thesis is to understand how interfacial parameters, such as the addition of organic additives, bulk pH or metal cations of the electrolyte, affect the relevant electrocatalytic reactions, i.e. electrochemical CO2 reduction reaction or hydrogen evolution reaction.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotores:Th.J.C. van Berkel, M. van Eck

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Biodiversity enables ecosystems to thrive through the synergy of functional differences among organisms. While human well-being strongly depends on biodiversity-driven ecosystem services, human actions are also at the root of current unprecedented biodiversity declines.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…

Onderwijs voor nieuwsgierige en ambitieuze studenten die meer uit hun studie willen halen!

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes

Teaching the Future: AI-Enhanced Education for Student Engagement and Ethical Learning.

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Promotor: Prof.dr. H.L.V. Linnartz

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Promotor: A.P.IJzerman Co-promotor: A. Bender

Cardiovascular diseases are still a major concern for the global health.

Congres/symposium

The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

Een lijst met wetenschappelijke publicaties samengesteld door het team van het TRIXY Expertisecentrum.

Andere COI-publicaties zijn te vinden op Leiden Law Blog, de Leiden Law Methods Portal en in het drop-down-menu hieronder.

Promotie

How were the Russians, under early modern conditions, able to incorporate this distant, undeveloped and, because frequent nomadic attacks, dangerous territory? And what role did the Kolyvan-Voskresensk plants play in this process?

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Understanding DNA repair mechanisms is essential for advancing plant biotechnology and crop improvement. This study investigates how double-strand breaks (DSBs), induced by CRISPR/Cas systems, are repaired in the model plant Arabidopsis thaliana, and how these processes influence Agrobacterium tumefaciens…

Carbonaceous asteroids preserve a record of early solar system processes, where minerals and organic molecules, like polycyclic aromatic hydrocarbons (PAHs), offer clues to planetary evolution and prebiotic chemistry.

Promotor: J. Schaye

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Curved single crystals provide variable, but well-defined surface structures.