Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

De onderzoeksgroep Governance of Crises bestudeert fenomenen, dynamieken en actoren die te maken hebben met crisisgovernance. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoeksgroep.

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Cardiovascular disease is the leading cause of death worldwide.

Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.

PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

De LUMC Alumni Vereniging is in 1996 opgericht om enerzijds de band tussen het Leids Universitair Medisch Centrum en zijn alumni te versterken, anderzijds om de band van de alumni onderling te versterken.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Dissolution processes – next to aggregation processes - play an important role for fate prediction and environmental risk assessment of metal-based nanoparticles (MNPs). It is challenging to predict the kinetics of the dissolution process of MNPs in complex systems such as we can find in in vivo and…

Hydrogen-based fuels are regarded as promising candidates for decarbonizing the maritime shipping sector.

In this thesis the links between allergy and intestinal health, the gut microbiome (GM), and external factors were studied by exploring the metabolome in longitudinal clinical studies and in vitro models.

Promotor: Prof.dr. C.U. Keller

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

Discover the master program Health, Ageing and Scoiety at Leiden University and contribute to a future proof health care system. Read more.

Jongeren nemen vaker risico dan kinderen en volwassenen. Dat komt doordat het beloningscentrum in hun hersenen veel actiever is als ze een beloning krijgen, ontdekte promovenda Barbara Braams. Daarnaast spelen persoonlijkheid, testosteron en sociale context een rol.

Promotie

Promotie

Promotie

Promotie

Promotie

Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.

The ultimate aim of this project is to improve cooperation between courts in different Member States.

Kunst en vrije tijd, Kunst en vrije tijd

Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

Onderstaand een overzicht van alle vakken die door de afdeling Economie worden verzorgd.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.

Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.

Leiden University’s Academic Challenge

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…