This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Promotor: Prof.dr. J.N. Kok

Promotor: T. H. Oosterkamp

Promotor: Prof.dr. M.K. Richardson

Promotor: Prof.dr. B.R. Katzy

Promotor: J. A. Bouwstra

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

In the emerging field of small-molecule RNA targeting, there is a growing demand for new high-throughput screening methods.

Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…

Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…

The zoo of detected exoplanets reveals both the uniqueness of our own Solar System and the complexity of planetary system formation, sparking fundamental questions about how planetary systems form and evolve.

Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

Promotor: Prof.dr. J. Kuiper

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Hieratic Papyrology

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

Op donderdag 16 november 2017 heeft Lalin Kovudhikulrungsri haar proefschrift ‘The Right to Travel by Air of Persons with Disabilities’ verdedigd. Haar promotoren zijn Prof.dr. P.M.J. Mendes De Leon en Prof.mr.dr. A.C. Hendriks.

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.

Promotor: Prof.dr. C.W.J. Beenakker

In dit artikel onderzoeken Bart Schuurman & Sarah Louise Carthy de verschillen tussen geradicaliseerde individuen en de algemene bevolking.

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

In de zaak Ferreira da Silva e Brito e.a./Estado portugues heeft het Hof van Justitie in het kader van overgang van onderneming expliciet de luchtvaartsector als kapitaalintensieve sector aangewezen. Hoe verhoudt het arrest zich tot het oordeel van het Gerechtshof Amsterdam over de overgang van de passagedivisie…

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

In this thesis, we address two problems concerning the tautological rings of the moduli space of curves.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Promotie

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Deze minor biedt een overzicht van het vakgebied Psychologie.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Dit boek neemt je stapsgewijs mee in het schrijven van een scriptie, met (voornamelijk) een focus op experimenteel onderzoek, dat het meest veel voorkomt. Door de stappen van experimenteel onderzoek in chronologische volgorde op te splitsen en bij elke stap tips te geven, hopen de auteurs enig houvast…

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.

Bij Studeren à la carte of toehoorderschap is er sprake van aanschuifonderwijs: u schuift aan bij een reguliere collegereeks, zonder dat u tentamen aflegt. Na afloop ontvangt u een certificaat van deelname. Hierop staan geen studieresultaten (er is immers geen tentamen afgelegd).

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.