This thesis investigates innovative and classical strategies in glycoconjugate vaccine development to address the growing threat of multidrug-resistant bacterial infections.

The vegetative growth period for leafy vegetables like lettuce is essential for yield and quality.

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Sinds de oprichting is LUC een college voor onderwijsontwikkeling en experimentatie. In de missie van het college wordt LUC beschreven als "een plek van innovatie op het gebied van didactiek, curriculumontwerp en studentwelzijn." Deze visie wordt toegepast via een studentgerichte benadering in het onderwijs…

Dit was het programma van De Kennisboomgaard 2025:

Promotie

Promotie

Promotie

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

De onderzoeksgroep War, Peace and Justice onderzoekt de samenhang tussen oorlog, vrede en gerechtigheid. Met een multidisciplinaire aanpak brengen onderzoekers en praktijkdeskundigen nieuwe inzichten in conflict, duurzame vrede en mensenrechten, met bijzondere aandacht voor gender en veiligheid.

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh

Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.

Het Leids Universitair Centrum voor de studie van Islam en Samenleving (LUCIS) is een interfacultair kenniscentrum dat een multidisciplinaire en vergelijkende benadering van islam en moslimsamenlevingen bevordert.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

This thesis surveys the intersection of computed tomography (CT) and machine learning (ML), treating CT as an ill-posed inverse problem shaped by object properties, imaging physics, and data limitations.

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Promotor: Prof.dr. D. Bouwmeester, Co-Promotor: M.J.A. de Dood

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

Computers worden steeds krachtiger en krijgen steeds ingewikkelder taken. Het Leiden Institute of Advanced Computer Science (LIACS) doet baanbrekend wetenschappelijk onderzoek en past nieuwe vindingen toe in actuele maatschappelijke vraagstukken.

Transforming governance for a just & sustainable future

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

The rapid expansion of research on human gut microbiome in recent decades has highlighted its role in human metabolism, immune regulation, and behavior.

Het ondersteunen van onderwijsprofessionals in hun doorlopende professionele ontwikkeling zien wij als een belangrijke taak. Voor het leveren van kwalitatief goed onderwijs zijn didactische vaardigheden net zo essentieel als vakkennis. Om dit te ondersteunen bieden wij een breed scala aan trainings-…

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

Wil je meer weten over de bacheloropleiding Security Studies en ervaren hoe het is om in Den Haag te studeren? De Universiteit Leiden biedt diverse voorlichtingsactiviteiten aan die je kunnen helpen bij je studiekeuze.

Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

What are the pressing issues of our time, and how can different disciplines come together to address them? Studium Generale and Leiden University College (LUC) present the Global Challenges series: events that bring together researchers from LUC and experts from other disciplines to tackle a shared…

Op Leiden University College (LUC) vindt samenwerking met internationale maatschappelijke partners plaats via onderzoek, onderwijs en stages. Dit resulteert in wederzijds waardevolle samenwerkingen met ngo’s, publieke instellingen en internationale partners.

We are very excited to announce our Sustainability Series for 2023-2024. Each month an interactive workshop will be organised that discusses a specific theme of sustainability. Interested about sustainability? Do not hesitate to sign up to our events !

Bestudeer alle aspecten van het menselijk leven in het verleden en plaats je kennis in een breder, historisch perspectief.

We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…

Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…

Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan

Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden

In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?