This monograph focuses on clustering of objects in high-dimensional data, given the restriction that the objects do not cluster on all the attributes, not even on a single subset of attributes, but often on different subsets of attributes in the data.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.

Promotor: Prof.dr. G.P. van Wezel

Statistical distributions in LCA and converting between different representations of these distributions.

In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.

Dit op casestudies gebaseerde Engelstalige boek over multivariate analyse voor gevorderde studenten in de geesteswetenschappen legt de nadruk op beschrijvende, exploratieve analyses van verschillende soorten datasets uit een breed scala van subdisciplines, waarbij het gebruik van multivariate analyse…

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Una Europa biedt veel verschillende mogelijkheden voor academici. Seed grants en workshops voor promovendi zijn slechts twee van de vele voorbeelden.

Workshop

In 2050 moet de overstap naar nieuwe, duurzame energiebronnen zijn voltooid. Wetenschappers van de Universiteit Leiden verrichten vanuit diverse disciplines uniek onderzoek dat bijdraagt aan deze transitie en de reductie van CO2.

Una Europa organiseert regelmatig oproepen voor startfinanciering, ook wel 'seed funding' genoemd. Universiteit Leiden biedt vaak extra financiering aan voor projecten waaraan Una Europa-universiteiten meedoen.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

Om de Leidse papyrologie te versterken is in 2014 de Papyrologie+ (spreek uit: papyrologie-plus) groep opgericht, een samenwerkingsverband van alle onderzoekers van de Leidse Universiteit die zich bezighouden met (Abnormaal-) Hiëratische, Demotische, Aramese, Griekse, Latijnse, Koptische en Arabische…

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

Met welke vaardigheden onderscheiden Geesteswetenschappers zich op de arbeidsmarkt? Hoe kunnen we studenten inzicht bieden in hun persoonlijke profiel? Kunnen zij inzicht in hun vaardigheden trainen en monitoren en daarmee hun kansen op de arbeidsmarkt vergroten?

Veel Nederlandse schaatsers en voetballers behoren tot de absolute wereldtop. Toch kunnen ze dankzij slimme statistische analyses wellicht nóg een beetje beter worden. De Universiteit Leiden werkt er samen met Delft en Amsterdam aan.

Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.

Woensdag 14 juli publiceerden Nederlandse astronomen een primeur in vakblad Nature. Het was hen als eersten ter wereld gelukt om isotopen te ontwaren in de damkring van een exoplaneet. Een ontdekking die ons meer kan leren over het ontstaan van planeten. Verschillende media schreven over de bijzondere…

Het boek biedt verschillende theoretische perspectieven om het proces van publieke sector hervormingen te onderzoeken. Daarnaast geeft het een overzicht van de belangrijkste trends in publieke sector hervormingen in Europa en de Verenigde Staten.

Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…