M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

Wat maakte het vroege islamitische rijk zo succesvol en hebben we het verhaal gemist door cruciaal bewijs te negeren? De Arabische veroveringen in de 7e eeuw veranderden de sociaal-politieke configuraties in het Middellandse Zeegebied en Eurazië voorgoed. Toch weten we niet echt hoe de Arabieren erin…

This thesis consists of two subjects, that are both a consequence of radiation pressure.

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

Students Practicing Citizen Journalism

This project uses archaeological, literary and epigraphic evidence to investigate urban development in Roman-period North Africa, compiling this in a GIS-linked database in order to analyse the development of urban settlement spatially over time.

Bij het Beleg van Leiden, in 1574, stierf een derde van de bevolking. Nog jaarlijks herdenkt de stad het einde van deze belegering met hutspot, haring en wittebrood. En Leiden staat niet alleen: steden zijn al duizenden jaren het toneel van strijd.

De Griekse papyrologie is de wetenschap die zich bezighoudt met het ontcijferen en bestuderen van alle teksten die in de Griekse taal op papyrus geschreven staan. Papyrus was het schrijfmateriaal van de oudheid en werd vervaardigd uit op elkaar gekleefde reepjes van de papyrusplant.

Een interdisciplinaire blik op omgaan met onzekerheid

Kunst en vrije tijd, Kunst en vrije tijd

The project

The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

How can we broaden youth participation in STEM Learning

Kunst en vrije tijd, Kunst en vrije tijd

Kunst en vrije tijd, Kunst en vrije tijd

Kunst en vrije tijd, Kunst en vrije tijd

Kunst en vrije tijd, Kunst en vrije tijd

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotor: Prof.dr. J.N. Kok

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

Promotor: Prof.dr. H.J.M. de Groot, Co-promotor: Francesco Buda

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Software development is a complex process. It is important that software products become stable and maintainable assets.

Promotor: A.P.IJzerman Co-promotor: A. Bender

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

The thesis is about the study of shell evolution of the Hydrocenidae of the genus Georissa. This thesis started with a general overview on the evolutionary process of animals due to ecological changes.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.