This dissertation consists of two parts, with the common theme

In dit artikel onderzoeken de onderzoekers hoe solidariteit begrepen kan worden, rekening houdend met de diversiteit van verhalen, ruimtes, praktijken, lichamen en tijdsperiodes in een stad.

Promotor: A.P. IJzerman

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Op 22 juni organiseerde het International Centre for Migration Policy Development (ICMPD) een webinar over de uitdagingen waarmee asielzoekers en vluchtelingen wereldwijd worden geconfronteerd als gevolg van de COVID-19 crisis.

Promotor: Prof.dr. E. Deprettere

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Eveline Crone bedankt haar geweldige collega's van het Brain and Development Research Center in Leiden. 'Ik ben zo dankbaar voor 15 fantastische jaren bij de Universiteit Leiden,' twittert Crone. De Erasmus Universiteit Rotterdam lonkt.

De Universiteit Leiden gaat als eerste universiteit in Europa samenwerken met de Asian Development Bank (ADB). De Aziatische ontwikkelingsbank wil meer een 'klimaatbank' worden, Leiden gaat daarbij helpen met onderzoek en onderwijs.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

This thesis focuses on addressing four research problems in designing embedded streaming systems.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

World Teachers Festival 2024 - Celebrating and exploring language, culture, diversity and criticality in teaching and learning

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Lezing

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

This dissertation investigates how the efficiency of Computed Tomography (CT) can be improved for dynamic scientific and industrial applications.

Loopbaan en solliciteren

Hoogleraar ontwikkelingspsychologie Eveline Crone is per 1 januari 2017 benoemd tot lid van de Sociaal-Wetenschappelijke Raad (SWR) van de Koninklijke Nederlandse Akademie van Wetenschappen (KNAW).

Promotor: P.M. Brakefield

Met welke vaardigheden onderscheiden Geesteswetenschappers zich op de arbeidsmarkt? Hoe kunnen we studenten inzicht bieden in hun persoonlijke profiel? Kunnen zij inzicht in hun vaardigheden trainen en monitoren en daarmee hun kansen op de arbeidsmarkt vergroten?

Eveline Crone is lang niet de enige professor puberbrein op het internationale FLUX-congres. Leiden was vier dagen lang het centrum van onderzoek naar hersenontwikkeling. Opvoeders en beleidsmakers ontmoetten wetenschappers tijdens het publiekssymposium op 18 september.

Eveline Crone legt aan presentator Charles Groenhuijsen uit waarom de ontwikkelingen in het brein het bijzondere gedrag van een puber verklaren.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

Loopbaan en solliciteren

The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…

Security is key to survival for any living organism: life is full of perils and threats, both physically, environmentally, and societally. Security challenges such as terrorism, natural disasters, and cybercrime rank among the most pressing issues of our time, affecting the security and safety of millions…

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.