Over a period of seven years, researchers from the International Brain Laboratory mapped 279 brain regions at the cellular level. Their findings are now published in Nature, with both data and software openly shared. Cognitive neuroscientist Anne Urai: 'Any researcher with a good question can make use…

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…

Researchers in Leiden have, for the first time, observed how a specialised enzyme helps bacteria stay alinve when oxygen levels are low, and how that process can be blocked. The discovery opens up new possibilities for targeted antibiotics.

Political scientists study topics that affect society, but their work often remains out of the spotlight. Not always: the research of Leiden political scientist Simon Otjes does have a visible impact.

Researchers at LUMC have made a breakthrough in understanding PALB2 mutations, an important cause of hereditary breast cancer.

Are you curious about how the human skeleton works? Discover this and more on 3 October in Leiden and on 4 October in The Hague.

Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.

Eight scientists from Leiden University have been awarded a grant by the Dutch Research Council (NWO). With this Vidi funding, the researchers can set up an innovative line of research and further expand their own research group over the next five years.

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Engineering, law, and business students came together in the LDE Space & Society Honours Programme to explore how space and society can mutually benefit each other. At the final event, they looked back upon a steep learning curve. ‘We tossed them into the water and they had to swim.’

Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…

A true shower of awards for students from the Faculty of Science during the annual KHMW Young Talent Awards ceremony. On Monday, 25 November, no less than nine first-year students received a prize for the best academic results in their first year. In addition, there were graduation prizes for master’s…

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.

On the university’s birthday, professors teach a class of 10 and 11-year-olds during Meet the Professor. The professors were bombarded with questions.

Building more in urban areas is, in most places in the Netherlands, the smartest way to tackle the housing crisis. This is evident from research conducted by Janneke van Oorschot, published in a partner journal of Nature. Remarkably, this does not have to come at the expense of green spaces in cities.…

With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…

Leiden researchers from different disciplines look together at complex social problems. What happens when they join forces with artists? The results could be seen on Tuesday 11 June during a unique exhibition. Take a look for yourself:

Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…