597 search results for “genetics” in the Public website
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Education
The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.
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Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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The social brain in middle childhood
A neurobiological perspective on individual differences in social competence
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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Direitos negados, patrimônios roubados
Desafios para a proteção dos conhecimentos tradicionais, dos recursos genéticos e das expressões culturais tradicionais dos povos indígenas no cenário internacional
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Mechanisms and consequences of horizontal gene transfer in cell wall-deficient cells of Kitasatospora viridifaciens
The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…
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Modeling the Genetic and Mechanical Interplay in Osteoarthritis
PhD defence
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Identifying novel genetic causes of familial colorectal cancer
PhD defence
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Unraveling the genetic architecture of migraine: exploring the vascular components
PhD defence
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Biodiversity & Evolution
Evolutionary and ecological interactions affect species on genetic and phenotypic levels. This theme aims to understand these processes at multiple levels: from molecules to genomes to populations and to communities. Our research focuses on evolutionary responses to anthropogenic change, the role of…
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Train your brain!
Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!
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Research
The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.
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Biodiversity research and expertise at the IBL
We investigate the processes underlying the patterns. We aim to explain biodiversity by investigating the distribution, function, development, and evolution of body forms, as well as physiological and behavioural variety among species. We collaborate with those specialized in describing, archiving,…
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Contact-induced change in Dolgan
This study explores the role of linguistic data in the reconstruction of Dolgan (pre)history by analyzing contact-induced changes and using them to infer information about the nature of the contact settings in which they occurred.
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Finding and valorizing new antibiotics using AI
Antibiotics are a class of medicine most people take for granted. But pathogenic bacteria are becoming more and more resistant to our antibiotics, and this poses a great challenge for future treatments. There is thus a great societal need to identify new molecules that can address new targets and be…
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Shy parent, shy child?
Delineating psychophysiological endophenotypes of social anxiety disorder
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Biodegradation of furan-based composite resin by novel enzymes
Can furan-based resisn be degraded by microbial enzymes in combination with mild pre-treatment?
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About the programme
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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Tom van der WelFaculty of Science
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Pim ArntzenFaculty of Science
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Participants
The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).
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Morphogenesis and protein production in Aspergillus niger
Promotor: Prof.dr. C.A.M.J.J. van den Hondel, Dr. ir. V. Meyer, Co-promotor: Dr. A.F.J. Ram
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Cancer Pathogenesis and Therapy
Cancer represents a formidable current and future global health challenge. The LUMC medical research profile Cancer Pathogenesis and Therapy charges this challenge by developing and implementing innovative patient-tailored, multimodal diagnostic methods and treatment modalities.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Role of epigenetics in long-term health effects of early life stress
Can epigenetic changes explain associations between early life stress and health outcomes?
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Standardized and reproducible measurement of decision-making in mice
In science, it is of vital importance that multiple studies corroborate the same result. Researchers therefore need to know all the details of previous experiments in order to implement the procedures as exactly as possible. However, this is becoming a major problem in neuroscience, as animal studies…
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Fire and Human Origins
Correctly interpreting the patterns of fire evidence in the archaeological record will illuminate the origin of human fire use.
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Born to be shy?
An international mega-analysis on the neurobiological link between inhibited temperament and social anxiety disorder
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Education
The information below concerns courses that our group teaches in Leiden.
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MARBLES - Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases
To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.
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About
The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.
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About the programme
The Biology programme offers 4 research-oriented specialisations corresponding with the research themes within the three institutes involved. You can choose a more practical-oriented specialisation if you would like to combine Biology with education, management business, or science communication.
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Applied Neuroscience in Human Development (MSc)
Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.
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The pre-Roman elements of the Sardinian lexicon
On the 12th of February, Cid Swanenvleugel successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Cid on this achievement!
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Expertise
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine. The available expertise extends…
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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Visualization of effector protein translocation from Agrobacterium tumefaciens into host cells
In our research protein translocation from Agrobacterium into yeast and plant cells is studied to obtain fundamental insights in the translocation process
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Our approach
Our group operates at the cross-roads of different disciplines: molecular and cellular microbiology, biochemistry, structural biology and biophysics. The group harbors expertise in a multitude of molecular and cellular approaches including:
- Prof Dr André Kessler
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Programme structure
Through courses and research projects, you are trained by experts in the field.
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Abstracts
We warmly welcome late abstracts for Poster Communications! Late abstracts submission closes on the 1st of August 2022.
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Virtual Neanderthals
This study presents an agent-based simulation model exploring the patterns of presence and absence of Late Pleistocene Neanderthals in western Europe.
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The prehistoric origin and spread of the Indo-Iranian languages
A linguistic test of hypotheses rooted in genetics and archaeology.
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Migration History in World History. Multidisciplinary Approaches | Studies in Global Social History, Volume: 3
Migration is the talk of the town. On the whole, however, the current situation is seen as resulting from unique political upheavals. Such a-historical interpretations ignore the fact that migration is a fundamental phenomenon in human societies from the beginning and plays a crucial role in the cultural,…
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CRISPR Cas-induced targeted mutagenesis with Agrobacterium mediated protein delivery
The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.
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The role of autophagy during carbon starvation in Aspergillus niger
Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.
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From wolf to dog
Morphometric and morphological differences have been used extensively in the past to study domestication of the wolf and the origin of dogs. Certainly before genetic testing was performed, these methods were the only means to diverge both groups. But still now, when aDNA cannot be extracted, morphometry…