The Leiden Institute of Chemistry (LIC) offers a unique tailor-made programme in Life Science and Technology. You can customize the programme to your own interests and ambitions with the help of your own personal mentor. Your study will focus on either a biomedical, molecular or biophysical approach…

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.

The modification of risk factors and related health behaviors lies at the very core of adequate cardiovascular risk management, yet evidence shows that the majority of people with cardiovascular disease (CVD) fail to achieve a healthy lifestyle in the long term. The main objective of this project is…

In the specialisation Health and Medical Psychology, part of the Master in Psychology, you will acquire knowledge on clinical and scientific topics in health promotion and disease prevention as well as practical training on clinical skills and behaviour change.

Producing offspring of a crop without sowing and that is even bigger than the parent plant. According to Leiden researchers this can be achieved by overstimulating a single gene that rejuvenates cells, including bringing them back to the embryonic phase.

Exploring the landscapes of mental health and cardiometabolic research.

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Five talks will be given during the Leiden Science Family Day: two children's lectures and three lectures for adults. Will you be there ?

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Leiden University and the city of The Hague are working closely together to increase the impact of our research and education in order to contribute as much as possible to the development of the city.

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

The Metabolic syndrome affects over 5 million people in the Netherlands. The HealthBox is an initiative from LUMC and NeLL to provide an innovative solution to help prevent and manage this chronic condition.

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

Decision support tool for cell therapy commercialization and business development

The Faculties of Leiden University have developed several themes for research cooperation between Leiden University and its Indonesian partners.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

A dental anthropological approach to foodways, health and disease, and crafting in the pre-Columbian Caribbean.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

The research area of this division is focused on the development of novel therapeutic modalities and novel concepts in early drug discovery, in order to better predict ligand-target interactions.

Promotor: Prof.dr. J.P. Abrahams

Cardiovascular diseases are still a major concern for the global health.

The effectiveness of the skin barrier underlies the outer layer of the skin: the stratum corneum (SC). However, in several skin diseases this barrier is impaired. In two inflammatory skin diseases, atopic eczema and Netherton syndrome, an increased level of monounsaturated fatty acids (MUFAs) has been…

Assistant Professor at the Metabolomics group, LUMC, The Nederlands

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

This focus area centres on promoting health and stimulating the physical, mental and social resilience of citizens.

With an ageing population it is becoming increasingly important to find means to repair cells, tissue and organs through regenerative medicine.

The aim of this project is to develop accurate but interpretable ensemble learning methods for high-dimensional multi-domain data.

A convolutional neural network (CNN) is a biologically inspired algorithm, highly capable at processing images and videos.

The research of the Biotherapeutic Delivery group led by Joachim Van Guyse focuses on developing novel polymer-based formulations for therapeutic nucleic acid and protein delivery. The research revolves around developing structure-activity relationships between the chemical structure of polymers, the…

Natashe Lemos Dekker addresses the experiences of family members of people with dementia as they expressed their sense of gradually losing the person with dementia in the article 'Anticipatory Grief in Dementia: An Ethnographic Study of Loss and Connection' published in Culture, Medicine, and Psychi…

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

In this thesis, we focus on novel proteins/mechanisms that regulate integrin-adhesion mediated mechano-transduction.

The Therapeutic Immunomodulation Group is led by Prof. Johan Kuiper. In this group we aim to identify novel immunologic targets and apply immunotherapy to inhibit or even prevent the development of atherosclerosis.

N-acylethanolamines (NAEs), including N-arachidonoylethanolamine (anandamide, AEA), N-palmitoylethanolamine (PEA) and N-oleoylethanolamine (OEA), are signaling lipids that play an important role in different physiological process.

The research connected to this topic is related to Work and health.

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…

Developing a clinical decision support tool that will make it easier for clinicians to personalise the treatment for patients with high blood pressure. The team is using AI, deep learning methods and patient cohort data from 11 European countries.

This multidisciplinary minor addresses the fascinating question how we, modern humans, got to be the way we are. Who were our ancestors? How does our morphology, genetic makeup, brain and behaviour relate to that of other species? How does our evolutionary past affect our susceptibility to diseases?…

PhD defence

PhD defence

PhD defence

PhD defence