Hoogleraar Koreastudies Remco Breuker onderzoekt dankzij deze subsidie van de European Research Council hoe beide Korea’s en China strijden om het oude Mantsjoerije.

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.

Promotor: C.J. ten Cate

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

Promotor: S.M. Verduyn Lunel

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Dit project identificeert en beschrijft de belangrijkste Indo-Europese talen en taaltakken en heeft tot dusver geresulteerd in twaalf delen, gepubliceerd als The Leiden Indo-European Etymological Dictionary Series (Brill, Leiden).

DNAmarkerpoint heeft als doel ecologie, evolutie en biodiversiteit beter te begrijpen door het bestuderen van modern en ancient DNA.

De master History van de Universiteit Leiden heeft een sterk internationaal karakter en focust op Europese- en niet-Europese geschiedenis vanuit een globale context.

Hoe hebben de purana's, als oude verhalen en anonieme teksten, bijgedragen aan de religieuze en politieke cultuur van het Sanskriet-wereldrijk? En hoe hebben verschillende mensen en groepen bijgedragen aan de verspreiding en ontwikkeling van deze teksten door de tijd en over verschillende regio's he…

Aan het einde van de vijftiende eeuw werden twee intrigerende christelijke epische gedichten geschreven in Virgilisch Latijn door de dichters Sannazaro en Vida. Ze deden dit in overeenstemming met de wensen van de paus. Deze epische gedichten, zowel geprezen als bekritiseerd door tijdgenoten, worden…

Om de Leidse papyrologie te versterken is in 2014 de Papyrologie+ (spreek uit: papyrologie-plus) groep opgericht, een samenwerkingsverband van alle onderzoekers van de Leidse Universiteit die zich bezighouden met (Abnormaal-) Hiëratische, Demotische, Aramese, Griekse, Latijnse, Koptische en Arabische…

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

Promotor: Prof.dr. J. Kuiper

I have studied the hot, diffuse gas around and between galaxies. Specifically, I have used the EAGLE numerical simulations of galaxy formation to predict the properties of this gas, and I have used those properties to predict specific observables: soft X-ray absorption and emission lines.

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Luuk de Ligt heeft met zijn projectvoorstel 'An Empire of 2000 cities: urban networks and economic integration in the Roman Empire' een prestigieuze ERC Advanced Grant binnengehaald. Het project, dat in 2013 van start zal gaan, gaat plaats bieden aan in ieder geval zes aio's en twee postdocs.

Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Na een succesvol afgeronde masteropleiding ontvang je de titel Master of Arts (MA).

Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Na een succesvol afgeronde masteropleiding ontvang je de titel Master of Arts (MA).

Wil je een volledige academische opleiding? Dan ga je na je bachelor door met een masteropleiding. Na een succesvol afgeronde masteropleiding ontvang je de titel Master of Arts (MA).

Commerciële bedrijven die gebruik willen maken van de expertise en faciliteiten worden doorverwezen naar LAB , de commerciële eenheid die verantwoordelijk is voor gespecialiseerd laboratoriumwerk.

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Promotor: Prof. dr. A.G.G.M. Tielens