Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Learning from small data sets in machine learning is a crucial challenge, especially when dealing with data imbalances and anomaly detection. This thesis delves into the challenges and methodologies of learning from small datasets in machine learning, with a particular focus on addressing data imbalances…

Promotor: Prof.dr. J.W.M. Frenken

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

Promotor: Prof.dr. M. de Jong

De Universiteit Leiden is sinds eind jaren negentig gevestigd in twee steden: Leiden en Den Haag. Ook de Faculteit der Rechtsgeleerdheid biedt op de Campus Den Haag onderwijs en onderzoek aan.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

Eveline Crone bedankt haar geweldige collega's van het Brain and Development Research Center in Leiden. 'Ik ben zo dankbaar voor 15 fantastische jaren bij de Universiteit Leiden,' twittert Crone. De Erasmus Universiteit Rotterdam lonkt.

The role of the interfacial environment during electrochemical reactions has been increasingly valued, especially for those reactions involving protons or hydroxyl ions.

In de ontwikkeling van de Humanities Campus worden zowel bij de gebouwen als bij het omringende gebied, zoveel mogelijk 'groene keuzes' gemaakt. De verduurzaming van de campus krijgt vorm aan de hand van beoordelingsmethode BREEAM-NL.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

Eveline Crone is één van de vier Leidse wetenschappers die in 2014 een Vici-beurs toegekend heeft gekregen uit de venieuwingsimpuls van de nationale wetenschapsfinancier NWO . Met deze subsidie van 1,5 miljoen euro kan zij een eigen onderzoeksgroep opzetten en promovendi aanstellen.​

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

In een reportage van NTR Academie vertelt hoogleraar neurocognitieve ontwikkelingspsychologie Eveline Crone uitgebreid over haar onderzoek bij adolescenten. Ze laat onder andere zien hoe hersenonderzoek bijdraagt aan het beantwoorden van vragen over typisch pubergedrag.

Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Kijk regelmatig op deze pagina voor meer informatie over het vergroten van de biodiversiteit aan de Universiteit Leiden.

Patients share valuable advice and experiences with their peers in online patient discussion groups.

Promotie

Hoogleraar Neurocognitieve ontwikkelingspsychologie Eveline Crone ontvangt een Ammodo KNAW Award. Dat maakten Ammodo, instituut voor kunst en wetenschap en de Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) op 25 januari bekend.

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

Eveline Crone, hoogleraar neurocognitieve ontwikkelingspsychologie aan de Universiteit Leiden, ontvangt de Dr. Hendrik Muller Prijs voor de Gedrags- en Maatschappijwetenschappen van de KNAW.

Hoogleraar neurocognitieve ontwikkelingspsychologie Eveline Crone is geïnstalleerd als lid van de Koninklijke Nederlandse Akademie van Wetenschappen (KNAW). Van 2008 tot 2013 was Crone lid van De Jonge Akademie. Momenteel is zij het jongste KNAW lid.

Hoogleraar Eveline Crone is op 13 januari toegetreden tot de Scientific Council van de European Research Council (ERC), de onderzoeksraad van de Europese Unie.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Eveline Crone verwacht dat de adolescentie een positieve invloed heeft op de sociale ontwikkeling. Zo denkt zij dat adolescenten beter leren samenwerken, delen en helpen. De komende tijd onderzoekt zij deze hypothese met een ERC Consolidator Grant.

Een onderzoek naar de ontwikkeling van prosociaal gedrag.

Jan van den Berg heeft zij proefschrift op 8 november 2018 verdedigd.

Het WARN-project heeft als doel te begrijpen waarom sommige waarschuwingen niet effectief genoeg zijn of niet tijdig de juiste besluitvormers bereiken om een crisis af te wenden.

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

Jaroslaw Kantorowicz and Rok Spruk onderzoeken de bijdrage van institutionele hervormingen aan economische groei.

Religion and ethnicity are inextricably linked in discourse within and about Central Asia. One common narrative suggests that as a result of differences between historically sedentary and nomadic populations, ethnic Tajiks and Uzbeks are naturally more religious and more likely to radicalise than their…

This thesis highlights the significant role of surface geometry and oxidation state in determining CO adsorption behavior on copper surfaces.

Promotie

In dit proefschrift onderzochten we hoe we kankerbehandelingen slimmer en veiliger kunnen doseren. Veel middelen worden nog volgens een “one size fits all”-schema gegeven, vaak gebaseerd op de maximaal verdraagbare dosis. Dat kan leiden tot onnodig veel bijwerkingen, behandelingonderbrekingen en hoge…

Promotie

The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…