In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Combinatorial games are games for two competing players, moving in a turn-by-turn fashion, in which there is no chance nor hidden information⁠. Chess, checkers and the simpler tic tac toe are well-known examples of this class of games, as well as game of go⁠.

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Promotor: C.J. ten Cate

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Promotor: P.D. Grünwald

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).

This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

Promotor: Prof.dr.ir. E. Deprettere

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

De onderzoeksgroep Cyber Security Governance bestudeert de impact van moderne technologie op governance, soevereiniteit, wetshandhaving en internationale betrekkingen, en levert toonaangevend academisch onderzoek en beleidsinzichten.

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Binnen de afdeling Publiek Management en Organisatie van het Instituut Bestuurskunde houden wij ons bezig met publieke organisaties en met de manier waarop managers en professionals daarbinnen hun werk doen.

Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.

Mechanical metamaterials are man-made materials which derive their unusual properties from their structure rather than their composition.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Promotores: S.J. Edixhoven, P.Parent

Workshop

Het Instituut Bestuurskunde van de Universiteit Leiden is gevestigd in het bestuurlijke hart van Nederland, in Den Haag. Vanuit deze centrale locatie verbindt het instituut wetenschappelijk onderzoek met de praktijk om actuele vraagstukken uit binnen- en buitenland aan te pakken.

Optimalisatie, werkingsmechanismen en voorspellers van het resultaat van lichttherapie bij depressie: Een multicenter gerandomiseerde trial

What are the pressing issues of our time, and how can different disciplines come together to address them? Studium Generale and Leiden University College (LUC) present the Global Challenges series: events that bring together researchers from LUC and experts from other disciplines to tackle a shared…